Mathematical modelling of phenotypic selection within solid tumours

DOI10.1007/978-3-319-96415-7_20MaRDI QIDQ2008680zbMATH OpenOpenAlexFDO

Authors T. Lorenzi, Alexander Lorz, Chandrasekhar Venkataraman, M. A. J. Chaplain

Publication date 26 November 2019

Full work available at URL http://sro.sussex.ac.uk/id/eprint/84688/1/__smbhome.uscs.susx.ac.uk_akj23_Documents_SRO%2001%2007%204.pdf

Mathematics Subject Classification ID

Medical applications (general) (92C50) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Integro-partial differential equations (35R09) Finite difference methods for initial value and initial-boundary value problems involving PDEs (65M06) Finite element, Rayleigh-Ritz and Galerkin methods for initial value and initial-boundary value problems involving PDEs (65M60) Computational methods for problems pertaining to biology (92-08) Cell biology (92C37)

Recommendations

• The role of spatial variations of abiotic factors in mediating intratumour phenotypic heterogeneity
• Modeling the effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors
• Spatio-temporal modelling of phenotypic heterogeneity in tumour tissues and its impact on radiotherapy treatment
• Evolutionary dynamics in vascularised tumours under chemotherapy: mathematical modelling, asymptotic analysis and numerical simulations
• Evolution of cancer cell populations under cytotoxic therapy and treatment optimisation: insight from a phenotype-structured model

Cited in

(8)

• A mathematical study of the influence of hypoxia and acidity on the evolutionary dynamics of cancer
• Mathematical modeling of the malignancy of cancer using graph evolution
• Spatio-temporal modelling of phenotypic heterogeneity in tumour tissues and its impact on radiotherapy treatment
• A mathematical study of the impact of cell plasticity on tumour control probability
• Dynamics of competing heterogeneous clones in blood cancers explains multiple observations -- a mathematical modeling approach
• Abrupt transitions to tumor extinction: a phenotypic quasispecies model
• Selection and assessment of phenomenological models of tumor growth
• The role of spatial variations of abiotic factors in mediating intratumour phenotypic heterogeneity

This page was built for publication: Mathematical modelling of phenotypic selection within solid tumours

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q2008680)