Evolutionary dynamics in vascularised tumours under chemotherapy: mathematical modelling, asymptotic analysis and numerical simulations
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Publication:2022476
evolutionary dynamicsintra-tumour heterogeneitymathematical oncologynon-local partial differential equationsresistance to chemotherapyvascularised tumours
Asymptotic behavior of solutions to PDEs (35B40) Nonlinear parabolic equations (35K55) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Integro-partial differential equations (35R09) Integro-partial differential equations (45K05) Medical applications (general) (92C50) Population dynamics (general) (92D25)
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Cited in
(23)- A mathematical model to study the effects of drug resistance and vasculature on the response of solid tumors to chemotherapy
- Vascular tumor growth and treatment: Consequences of polyclonality, competition and dynamic vascular support
- Evolution of a mathematical model of an aggressive-invasive cancer under chemotherapy
- Mathematical modelling of phenotypic selection within solid tumours
- A mathematical study of the influence of hypoxia and acidity on the evolutionary dynamics of cancer
- Spatio-temporal modelling of phenotypic heterogeneity in tumour tissues and its impact on radiotherapy treatment
- A mathematical dissection of the adaptation of cell populations to fluctuating oxygen levels
- Mathematical modeling of chemotherapy strategies in vascular tumor growth using nanopar\-ti\-cles
- A mathematical model for the dynamics of cancer hepatocytes under therapeutic actions
- Evolutionary dynamics of cancer cell populations under immune selection pressure and optimal control of chemotherapy
- Nonlinear analysis of a model of vascular tumour growth and treatment
- Modeling the emergence of phenotypic heterogeneity in vascularized tumors
- Discrete and continuum phenotype-structured models for the evolution of cancer cell populations under chemotherapy
- Measure framework for the pure selection equation: global well posedness and numerical investigations
- Deep learning approximations for non-local nonlinear PDEs with Neumann boundary conditions
- Optimal control in reducing side effects during and after chemotherapy of solid tumors
- Mathematical modeling and quantitative analysis of phenotypic plasticity during tumor evolution based on single-cell data
- The development of drug resistance in metastatic tumours under chemotherapy: an evolutionary perspective
- A mathematical model for cancer dynamics with treatment and saboteur bacteria
- Reducing phenotype-structured partial differential equations models of cancer evolution to systems of ordinary differential equations: a generalised moment dynamics approach
- Investigating tumour responses to combinations of radiotherapy and hyperthermia
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- Hypoxia-resistance heterogeneity in tumours: the impact of geometrical characterization of environmental niches and evolutionary trade-offs. A mathematical approach
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