Evolutionary dynamics in vascularised tumours under chemotherapy: mathematical modelling, asymptotic analysis and numerical simulations (Q2022476)
From MaRDI portal
scientific article
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Evolutionary dynamics in vascularised tumours under chemotherapy: mathematical modelling, asymptotic analysis and numerical simulations |
scientific article |
Statements
Evolutionary dynamics in vascularised tumours under chemotherapy: mathematical modelling, asymptotic analysis and numerical simulations (English)
0 references
29 April 2021
0 references
This work reports a mathematical model, which takes into account spontaneous epimutations introduced as the diffusion term within the equation for phenotypic distribution density and effects of the oxygen concentration and the concentration of the chemotherapeutic agent modelled as a non-local integral reaction term. The dynamics of control substances is described with partial integro-differential equations too. The introduced model is studied analytically as well as numerically, and the illustrated discussion of phenotypic control is provided.
0 references
vascularised tumours
0 references
evolutionary dynamics
0 references
intra-tumour heterogeneity
0 references
resistance to chemotherapy
0 references
mathematical oncology
0 references
non-local partial differential equations
0 references
0 references
0 references
0 references
0 references
0 references
0 references
0 references
0 references
0 references
