Modelling and identification of drug diffusion in brain

DOI10.1016/0895-7177(93)90020-YMaRDI QIDQ1310205zbMATH OpenFDO

Authors A. Bellagoun, Yves Cherruault, A. Meulemans

Publication date 14 March 1994

Published in Mathematical and Computer Modelling (Search for Journal in Brave)

zbMATH Keywords

global optimizationpartial differential equationcontinuity equationdiffusivitymass balanceanticancerous molecules across cerebral tissuecapillary transfer constantcerebral transportconcentration curvesone-dimensional transport

Mathematics Subject Classification ID

Medical applications (general) (92C50) PDEs in connection with biology, chemistry and other natural sciences (35Q92)

Recommendations

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Cites work

• scientific article; zbMATH DE number 3425396 (Why is no real title available?)
• A New Method for Global Optimisation (Alienor)
• A SIMPLE METHOD FOR OPTIMIZATION
• Cubic spline approximation techniques for parameter estimation in distributed systems
• Fully discrete approximation methods for the estimation of parabolic systems and boundary parameters
• Oxygen tension profiles in tumors predicted by a diffusion with absorption model involving a moving free boundary

Cited in

(9)

• Identification of an anticancerous drug model in brain tissues using Adomian/Alienor methods
• scientific article; zbMATH DE number 1254064 (Why is no real title available?)
• Improving the prediction of local drug distribution profiles in the brain with a new 2D mathematical model
• A diffusion model for mass transport in brain tissue
• Diffusion-reaction model for mass transportation in brain tissues
• scientific article; zbMATH DE number 426430 (Why is no real title available?)
• Fitting Density Functions and Diffusion Tensors to Three-Dimensional Drug Transport within Brain Tissue
• An optimization approach to the estimation of effective drug diffusivity: From a planar disc into a finite external volume
• Theoretical effects of radioligand diffusional gradients and microscopic neuroreceptor distribution in in vivo kinetic studies

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