One-dimensional multicomponent hemodynamics
blood vessel with elastic wallsflow problemglobal existenceinitial--boundary value problemmass Lagrangian variablesmulticomponent fluidone-dimensional hemodynamics
Existence problems for PDEs: global existence, local existence, non-existence (35A01) Uniqueness problems for PDEs: global uniqueness, local uniqueness, non-uniqueness (35A02) Classical solutions to PDEs (35A09) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Linear elasticity with initial stresses (74B10) Fluid-solid interactions (including aero- and hydro-elasticity, porosity, etc.) (74F10) Physiological flows (76Z05) Physiological flow (92C35)
A one-dimensional model of blood flow in an artery has been developed in many works (in particular in [\textit{J. R. Womersley}, Philos. Mag., VII. Ser. 46, 199--221 (1955; Zbl 0064.43903); \textit{J. W. Lambert}, ``On the nonlinearities of fluid flow in nonrigid tubes, J. Franklin Inst. 266, No. 2, 83--102 (1958); \textit{T. J. R. Hughes} and \textit{J. Lubliner}, Math. Biosci. 18, 161--170 (1973; Zbl 0262.92004); \textit{D. Bessems} et al., J. Fluid Mech. 580, 145--168 (2007; Zbl 1175.76171); \textit{R. Raghu} et al., ``Comparative study of viscoelastic arterial wall models in nonlinear one-dimensional finite element simulations of blood flow, J. Biomech. Eng. 133, No. 8, 5--32 (2011); \textit{G. Mulder} et al., ``Patient-specific modeling of cerebral blood flow: geometrical variations in a 1D model, Cardiovasc. Eng. Tech. 2, 334--348 (2011)]). Under certain assumptions, the generalization of this model to the multicomponent case is studied. After the transition from the Euler coordinate to the mass Lagrangian coordinates, a system of differential equations is obtained, which coincides in formulation with the system of differential equations of one-dimensional polytropic flows of viscous compressible multicomponent fluid. [\textit{A. E. Mamontov} and \textit{D. A. Prokudin}, Sib. Zh. Chist. Prikl. Mat. 17, No. 2, 52--68 (2017; Zbl 1438.76030); translation in J. Math. Sci., New York 231, No. 2, 227--242 (2018)]. The problem of initial-boundary value for this system is investigated and the conditions of existence and uniqueness of the classical solution are established.
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