Pbn-STAC: deep reinforcement learning-based framework for cellular reprogramming

DOI10.1016/J.TCS.2025.115382MaRDI QIDQ6956043zbMATH OpenFDO

Authors Andrzej Mizera, Jakub Zarzycki

Publication date 21 July 2025

Published in Theoretical Computer Science (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/J.TCS.2025.115382

zbMATH Keywords

Boolean networkscellular reprogrammingdeep reinforcement learninggene regulatory networksnetwork control

Mathematics Subject Classification ID

Artificial neural networks and deep learning (68T07) Cell biology (92C37) Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

Cites work

• \({\mathcal Q}\)-learning
• Boolean dynamics revisited through feedback interconnections
• Identification of genetic networks by strategic gene disruptions and gene overexpressions under a Boolean model.
• Phenotype control of partially specified Boolean networks
• Reinforcement learning. An introduction
• Sequential temporary and permanent control of Boolean networks

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