| Publication | Date of Publication | Type |
|---|
Blinded-into-unblinded interim analyses for clinical trials with time-to-event endpoints
Biometrical Journal | 2026-08-31 | Paper |
Two-stage designs for cross-over bioequivalence trials
Statistics in Medicine | 2025-11-10 | Paper |
Methods for proper handling of overrunning and underrunning in phase II designs for oncology trials
Statistics in Medicine | 2025-11-07 | Paper |
Opportunities and challenges of combined effect measures based on prioritized outcomes
Statistics in Medicine | 2025-09-12 | Paper |
Comments on: ``Hypothesis testing for two-stage designs with over or under enrollment''
Statistics in Medicine | 2025-07-08 | Paper |
Utility-based optimization of phase II/III programs
Statistics in Medicine | 2025-06-30 | Paper |
Investigations on non-inferiority -- the Food and Drug Administration draft guidance on treatments for nosocomial pneumonia as a case for exact tests for binomial proportions
Statistics in Medicine | 2025-06-17 | Paper |
Assessment of statistical significance and clinical relevance
Statistics in Medicine | 2025-06-02 | Paper |
Utility-based optimization of Fujikawa’s basket trial design – Pre-specified protocol of a comparison study
PLOS One | 2025-05-28 | Paper |
Point estimation in adaptive enrichment designs
Statistics in Medicine | 2025-04-16 | Paper |
Simulation-based adjustment after exploratory biomarker subgroup selection in phase II
Statistics in Medicine | 2025-04-14 | Paper |
Point estimation and p-values in phase II adaptive two-stage designs with a binary endpoint
Statistics in Medicine | 2025-04-04 | Paper |
Comments on: ``Sample size adaptation designs and efficiency comparison with group sequential designs''
Statistics in Medicine | 2025-02-21 | Paper |
A weighted combined effect measure for the analysis of a composite time-to-first-event endpoint with components of different clinical relevance
Statistics in Medicine | 2025-02-07 | Paper |
| drugdevelopR | 2025-01-14 | Software |
New results on optimal conditional error functions for adaptive two-stage designs
Journal of Applied Statistics | 2025-01-14 | Paper |
A Basket Trial Design Based on Power Priors
Statistics in Biopharmaceutical Research | 2024-11-11 | Paper |
Optimization of the two-stage group sequential three-arm gold-standard design for non-inferiority trials
Statistics in Medicine | 2024-10-30 | Paper |
Comments on ``Adaptive sample size modification in clinical trials: start small then ask for more?''
Statistics in Medicine | 2024-10-29 | Paper |
A new conditional performance score for the evaluation of adaptive group sequential designs with sample size recalculation
Statistics in Medicine | 2024-10-29 | Paper |
Optimal planning of adaptive two-stage designs
Statistics in Medicine | 2024-10-29 | Paper |
Simulation and data-generation for random-effects network meta-analysis of binary outcome
Statistics in Medicine | 2024-10-28 | Paper |
A variational approach to optimal two-stage designs
Statistics in Medicine | 2024-10-28 | Paper |
What makes a biostatistician?
Statistics in Medicine | 2024-10-28 | Paper |
Point estimation, confidence intervals, and P-values for optimal adaptive two-stage designs with normal endpoints
Statistics in Medicine | 2024-10-14 | Paper |
Using real-world data to predict health outcomes -- the prediction design: application and sample size planning
Biometrical Journal | 2024-08-28 | Paper |
Optimization of adaptive designs with respect to a performance score
Biometrical Journal | 2023-12-15 | Paper |
Monotonicity conditions for avoiding counterintuitive decisions in basket trials
Biometrical Journal | 2023-12-15 | Paper |
Using independent cross‐sectional survey data to predict post‐migration health trajectories among refugees by estimating transition probabilities and their variances
Biometrical Journal | 2023-12-15 | Paper |
Categories, components, and techniques in a modular construction of basket trials for application and further research
Biometrical Journal | 2023-11-27 | Paper |
Optimization of the two‐stage group sequential three‐arm gold‐standard design for non‐inferiority trials
Statistics in Medicine | 2022-12-28 | Paper |
A note on the shape of sample size functions of optimal adaptive two-stage designs
Communications in Statistics: Theory and Methods | 2022-05-30 | Paper |
Optimal planning of adaptive two‐stage designs
Statistics in Medicine | 2021-03-18 | Paper |
The adoptr Package: Adaptive Optimal Designs for Clinical Trials in R
Journal of Statistical Software | 2021-01-01 | Paper |
Optimal designs for phase II/III drug development programs including methods for discounting of phase II results
BMC Medical Research Methodology | 2020-10-09 | Paper |
Sample size recalculation in internal pilot study designs: a review
Biometrical Journal | 2020-09-24 | Paper |
| A bootstrap procedure for adaptive selection of the test statistic in flexible two-stage designs | 2020-09-22 | Paper |
A comparison of procedures for adaptive choice of location tests in flexible two-stage designs
Biometrical Journal | 2020-09-22 | Paper |
Blinded sample size recalculation for normally distributed outcomes using long- and short-term data
Biometrical Journal | 2020-09-22 | Paper |
Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials
Springer Series in Pharmaceutical Statistics | 2020-08-17 | Paper |
Adjustment for exploratory cut-off selection in randomized clinical trials with survival endpoint
Biometrical Journal | 2020-07-17 | Paper |
Integrated evaluation of targeted and non-targeted therapies in a network meta-analysis
Biometrical Journal | 2020-07-17 | Paper |
Optimal Designs for Multi-Arm Phase II/III Drug Development Programs
Statistics in Biopharmaceutical Research | 2020-01-30 | Paper |
Optimal sample size allocation and go/no-go decision rules for phase II/III programs where several phase III trials are performed
Biometrical Journal | 2019-07-02 | Paper |
A variational approach to optimal two‐stage designs
Statistics in Medicine | 2019-07-01 | Paper |
A closer look at the effect of preliminary goodness-of-fit testing for normality for the one-sample \(t\)-test
British Journal of Mathematical and Statistical Psychology | 2018-12-05 | Paper |
Consistency-adjusted alpha allocation methods for a time-to-event analysis of composite endpoints
Computational Statistics and Data Analysis | 2018-11-23 | Paper |
Optimal planning of phase II/III programs for clinical trials with multiple endpoints
Pharmaceutical Statistics | 2018-04-26 | Paper |
Test-compatible confidence intervals for adaptive two-stage single-arm designs with binary endpoint
Biometrical Journal | 2018-02-09 | Paper |
An expected power approach for the assessment of composite endpoints and their components
Computational Statistics and Data Analysis | 2017-06-30 | Paper |
Assessing additional benefit in noninferiority trials
Biometrical Journal | 2016-03-14 | Paper |
Utility‐based optimization of phase II/III programs
Statistics in Medicine | 2015-08-09 | Paper |
Optimal adaptive two-stage designs for phase II cancer clinical trials
Biometrical Journal | 2013-11-19 | Paper |
Sample size calculation and blinded sample size recalculation in clinical trials where the treatment effect is measured by the relative risk
Communications in Statistics. Simulation and Computation | 2013-06-13 | Paper |
Sample size calculations for noninferiority trials with Poisson distributed count data
Biometrical Journal | 2013-04-30 | Paper |
Improving the flexibility and efficiency of phase II designs for oncology trials
Biometrics | 2012-11-19 | Paper |
Curtailment in single-arm two-stage phase II oncology trials
Biometrical Journal | 2012-09-13 | Paper |
Supporting information blinded sample size recalculation in multicentre trials with normally distributed outcome
Biometrical Journal | 2010-09-21 | Paper |
Configural frequency analysis and association analyses in contingency tables
Computational Statistics and Data Analysis | 2008-11-26 | Paper |
Including long- and short-term data in blinded sample size recalculation for binary endpoints
Computational Statistics and Data Analysis | 2008-11-26 | Paper |
Monitoring Continuous Long-Term Outcomes in Adaptive Designs
Communications in Statistics. Simulation and Computation | 2005-07-18 | Paper |
Procedures for testing multiple endpoints in clinical trials: an overview
Journal of Statistical Planning and Inference | 2002-02-18 | Paper |
A note on change point estimation in dose-response trials
Computational Statistics and Data Analysis | 2001-08-20 | Paper |
APPROXIMATE SAMPLE SIZES FOR TESTING HYPOTHESES ABOUT THE RATIO AND DIFFERENCE OF TWO MEANS
Journal of Biopharmaceutical Statistics | 2001-06-05 | Paper |
| Configural Frequency Analysis (CFA) Revisited — a New Look at an Old Approach | 2000-03-21 | Paper |
| scientific article; zbMATH DE number 1332897 (Why is no real title available?) | 2000-02-21 | Paper |
| scientific article; zbMATH DE number 1332899 (Why is no real title available?) | 1999-11-09 | Paper |
A unifying approach for confidence intervals and testing of equivalence and difference
Biometrika | 1998-03-11 | Paper |
On the Use of the Upper Confidence Limit for the Variance from a Pilot Sample for Sample Size Determination
Biometrical Journal | 1998-01-05 | Paper |
