Sequential activation of metabolic pathways: a dynamic optimization approach

DOI10.1007/S11538-009-9427-5MaRDI QIDQ1048264zbMATH OpenOpenAlexWikidataFDO

Authors Diego A. Oyarzún, Brian P. Ingalls, Dimitrios Kalamatianos, Richard H. Middleton

Publication date 11 January 2010

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution-NonCommercial 4.0 International

Full work available at URL https://doi.org/10.1007/s11538-009-9427-5

zbMATH Keywords

dynamic optimizationmetabolic regulationmetabolic dynamics

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Dynamic programming (90C39) Dynamic programming in optimal control and differential games (49L20) Cell biology (92C37) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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Cites work

• scientific article; zbMATH DE number 3619680 (Why is no real title available?)
• scientific article; zbMATH DE number 1090658 (Why is no real title available?)
• Is maximization of molar yield in metabolic networks favoured by evolution?
• Time ordering of gene coexpression

Cited in

(13)

• Enzyme allocation problems in kinetic metabolic networks: optimal solutions are elementary flux modes
• Dynamic optimization of metabolic networks coupled with gene expression
• Exact probability distributions of selected species in stochastic chemical reaction networks
• Sensitivity analysis of a linear and unbranched chemical process with \(n\) steps
• Cyclic coordinate descent in a class of bang-singular-bang problems
• Influence of enzyme production dynamics on the optimal control of a linear unbranched chemical process
• Optimal performance of the tryptophan operon of \textit{E. coli}: a stochastic, dynamical, mathematical-modeling approach
• Dynamical analysis and optimization of a generalized resource allocation model of microbial growth
• CMMSE-17: general analytical laws for metabolic pathways
• Mixed-integer minimax dynamic optimization for structure identification of glycerol metabolic network
• On dynamically generating relevant elementary flux modes in a metabolic network using optimization
• Optimal control of a linear unbranched chemical process with \(n\) steps: the quasi-analytical solution
• Solving linear unbranched pathways with Michaelis-Menten kinetics using the Lambert \(W\)-function

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Uses Software

• PROPT
• TOMSYM

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