Minimal sampling schedules for identification of dynamic models of metabolic systems of clinical interest: Case studies for two liver function tests

DOI10.1016/0025-5564(82)90037-2zbMATH Open0515.92003OpenAlexW1972995340MaRDI QIDQ1052255FDOQ1052255

Authors: A. Ruggeri, Claudio Cobelli, Joseph J. III DiStefano 

Publication date: 1983

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(82)90037-2

zbMATH Keywords

Monte Carlo simulationcase studiesdynamic models of metabolic systemsliver function testsminimal sampling schedules

Mathematics Subject Classification ID

Medical applications (general) (92C50) System identification (93B30) Physiological, cellular and medical topics (92Cxx)

Cites Work

• Dynamic system identification. Experiment design and data analysis
• A Comparison of Algorithms for Constructing Exact D-Optimal Designs
• Optimal nonuniform sampling interval and test-input design for identification of physiological systems from very limited data

Cited In (4)

• Qualitative and quantitative experiment design for phenomenological models - a survey
• Incorporating prior parameter uncertainty in the design of sampling schedules for pharmacokinetic parameter estimation experiments
• Optimal input design for identification of compartmental models. Theory and application to a model of glucose kinetics
• Modeling and identification of endocrine-metabolic systems. Theoretical aspects and their importance in practice

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