Cell mass concentration variance resulting from fluctuations in the incoming nutrient concentration to a chemostat

DOI10.1007/BF02459920MaRDI QIDQ1059569zbMATH OpenOpenAlexFDO

Authors J. Blot

Publication date 1985

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/bf02459920

zbMATH Keywords

cellular responsechemostatincoming nutrient concentration fluctuationssingle microbial populationsteady-state variance of cell mass concentrationwhite noise process

Mathematics Subject Classification ID

Physiological, cellular and medical topics (92Cxx) Population dynamics (general) (92D25) Chemistry (92Exx)

Review text

The cellular response in terms of steady-state variance of cell mass concentration to fluctuations in incoming nutrient concentration to a chemostat has been examined. A white noise process is assumed to describe incoming nutrient concentration fluctuations and the variance of cell mass concentration has been found to depend on cell yield (a lumped measure of nutrient concentration fluctuation magnitude and lifetime) and two system time constants.

Recommendations

• Fluctuations in circulating cell numbers following chemotherapy or bone marrow transplant
• Dynamic sensitivity of a chemostat for a microbial reaction with substrate and product inhibition
• Investigation of steady-state oscillatory processes in a chemostat
• Analysis of a chemostat model with variable yield coefficient
• Break-even concentration and periodic behavior of a stochastic chemostat model with seasonal fluctuation

Cites work

• A stochastic analysis of the growth of competing microbial populations in a continuous biochemical reactor
• Classical Noise IV: Langevin Methods
• Fluctuations from the Nonequilibrium Steady State
• Stochastic Problems in Physics and Astronomy

Cited in

(3)

• Fluctuations in circulating cell numbers following chemotherapy or bone marrow transplant
• Dynamic shear-stress-enhanced rates of nutrient consumption in gasliquid semi-continuous-flow suspensions
• The dynamics of single-substrate continuous cultures: the role of ribosomes

This page was built for publication: Cell mass concentration variance resulting from fluctuations in the incoming nutrient concentration to a chemostat

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q1059569)