Excitation wave propagation within narrow pathways: Geometric configurations facilitating unidirectional block and reentry

DOI10.1016/0167-2789(92)90071-TMaRDI QIDQ1196047zbMATH OpenOpenAlexFDO

Authors Boris Kogan, Walter J. Karplus, Brian S. Billett, William G. Stevenson

Publication date 18 January 1993

Published in Physica D (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/0167-2789(92)90071-t

zbMATH Keywords

computer simulation approachconduction propertiesheartinfarct scarsmodified FitzHugh-Nagumo equationsnarrow pathways of 2D excitable mediapropagation of excitation wavesreentrant arrhythmiasreentryunidirectional block

Mathematics Subject Classification ID

Physiology (general) (92C30) Medical applications (general) (92C50)

Review text

The propagation of excitation waves in narrow pathways of 2D excitable media through regions of impermeable media and decreased excitability media is investigated as a model of reentrant arrhythmias in the heart. Arrhythmia occurrences are common in the presence of infarct scars where regions of normal tissue are interspersed with inexcitable ones. Propagation through narrow pathways with three idealized geometric configurations are considered: propagation through narrow paths with either parallel borders, tapered borders, or a combination of these. The focus of this study is on the conditions for unidirectional block and reentry appearance. It is shown that in narrow paths with only parallel borders unidirectional block is impossible, regardless of the properties of the border media. In this case only bidirectional propagation or block is possible, depending on the pathway width. Unidirectional block can occur, however, when the narrow path has a tapered shape. Waves propagating from the wide end of the pathway die out at the narrow end, while waves propagating in the opposite direction are able to pass through.

Recommendations

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Cites work

• A Geometrical Theory for Spiral Waves in Excitable Media
• A hybrid method for solving partial differential equations of parabolic type
• scientific article; zbMATH DE number 44641 (Why is no real title available?)
• On the diffraction of autowaves
• On the formation of circulating patterns of excitation in anisotropic excitable media
• RE-ENTRANT ROTATING WAVES IN A BEELER–REUTER BASED MODEL OF TWO-DIMENSIONAL CARDIAC ELECTRICAL ACTIVITY
• The simplified FitzHugh-Nagumo model with action potential duration restitution: Effects on 2D wave propagation

Cited in

(3)

• Measurements of curvature in an ionic model of cardiac tissue
• Wavefront-obstacle interactions and the initiation of reentry in excitable media
• A THEORETICAL APPROACH OF THE PROPAGATION THROUGH GEOMETRICAL CONSTRAINTS IN CARDIAC TISSUE

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