Interpretation of Scatchard plots for aggregating receptor systems

DOI10.1016/0025-5564(92)90090-JzbMath0760.92006OpenAlexW2059852109WikidataQ52411398 ScholiaQ52411398MaRDI QIDQ1205290

Carla Wofsy, Byron Goldstein

Publication date: 1 April 1993

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(92)90090-j

zbMATH Keywords

membrane proteinsmonoclonal antibodiesligand bindingaggregation of cell surface receptorsaggregation of heterologous receptorsantibody-induced co-cross-linking of cell surface antibodiescellular responsescross-linking of cell surface antibodiescross-linking of monovalent cell surface proteinsequilibrium bindinginterleukinligand-enhanced aggregation of identical epidermal growth factor receptorsreceptor affinityScatchard plot

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Physiology (general) (92C30)

Related Items

Equilibrium binding of multivalent ligands to cells: Effects of cell and receptor density

Cites Work

• Ring formation in divalent-receptor-divalent-ligand interaction: Pseudocooperative shapes of Scatchard plots
• Receptor clustering on a cell surface. I. Theory of receptor cross- linking by ligands bearing two chemically identical functional groups

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