Optimal strategies in immunology. I: B-cell differentiation and proliferation

DOI10.1007/BF00275065MaRDI QIDQ1237008zbMATH OpenOpenAlexWikidataFDO

Authors Alan S. Perelson, Majdedin Mirmirani, George F. Oster

Publication date 1976

Published in Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/bf00275065

Mathematics Subject Classification ID

Population dynamics (general) (92D25) Existence of optimal solutions belonging to restricted classes (Lipschitz controls, bang-bang controls, etc.) (49J30) General biology and biomathematics (92B05)

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• A dynamical model of humoral immune response
• Competition between phenotypes
• The kinetics of hemolytic plaque formation. V: The influence of geometry on plaque growth

Cited in

(14)

• A threshold model simulating humoral immune response to replicating antigens
• Delays do not cause oscillations in a corrected model of humoral mediated immune response
• Stochastic optimal therapy for enhanced immune response
• Optimal control applications in biomedical engineering-a survey
• Competition, kin selection, and evolutionary stable strategies
• A computational approach for understanding immune response to multiple epitopes based on optimal control formulation
• Reaction diffusion equations and the chronification of liver infections
• Approximate solution of a model of biological immune responses incorporating delay
• Optimal strategies in immunology III. The IgM-IgG switch
• Optimal control of innate immune response
• Memory in idiotypic networks due to competition between proliferation and differentiation
• Dynamic optimization of host defense, immune memory, and post-infection pathogen levels in mammals
• Effects of antibodies and cytotoxic T-lymphocytes on cancer: a mathematical study
• Modeling inoculum dose dependent patterns of acute virus infections

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