A stem cell model for carcinogenesis

DOI10.1016/0025-5564(94)90053-1zbMath0795.92011WikidataQ38511148 ScholiaQ38511148MaRDI QIDQ1325042

Annette Kopp-Schneider, Christopher J. Portier

Publication date: 7 July 1994

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(94)90053-1

zbMATH Keywords

Kolmogorov equations; clonal expansion; cumulative distribution; reflecting barrier; intermediate cells; malignant tumors; number of detectable intermediate cell clones; papilloma formation; two-stage model of carcinogenesis

Mathematics Subject Classification ID

60J85: Applications of branching processes

92C50: Medical applications (general)

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A model for hepatocarcinogenesis treating phenotypical changes in focal hepatocellular lesions as epigenetic events, Two stage model for carcinogenesis: Number and size distributions of premalignant clones in longitudinal studies, Calculating tumor incidence rates in stochastic models of carcinogenesis

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