A mixture model approach for the analysis of microarray gene expression data.

DOI10.1016/S0167-9473(01)00046-9zbMath1119.62371WikidataQ127631370 ScholiaQ127631370MaRDI QIDQ1608619

Cheol-Koo Lee, Gary L. Gadbury, David B. Allison, Moonseong Heo, José R. Fernández

Publication date: 8 August 2002

Published in: Computational Statistics and Data Analysis (Search for Journal in Brave)

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10)

Related Items

Testing homogeneity in a heteroscedastic contaminated normal mixture, On a resampling approach for tests on the number of clusters with mixture model-based clustering of tissue samples, Omnibus testing and gene filtration in microarray data analysis, Multiple-Testing Strategy for Analyzing cDNA Array Data on Gene Expression, Consistency of a recursive estimate of mixing distributions, A parametric model to estimate the proportion from true null using a distribution for \(p\)-values, Inference after checking multiple Bayesian models for data conflict and applications to mitigating the influence of rejected priors, Estimation of empirical null using a mixture of normals and its use in local false discovery rate, Stochastic approximation and Newton's estimate of a mixing distribution, Deriving and comparing the distribution for the number of false positives in single step methods to control \(k\)-FWER, A probabilistic framework for microarray data analysis: fundamental probability models and statistical inference, Size, power and false discovery rates, Linear Score Tests for Variance Components in Linear Mixed Models and Applications to Genetic Association Studies, A multivariate version of the Benjamini-Hochberg method, Hadamard matrix methods in identifying differentially expressed genes from microarray experi\-ments, On estimating the proportion of true null hypotheses for false discovery rate controlling procedures in exploratory DNA microarray studies, Internal validation inferences of significant genomic features in genome-wide screening, A mixture model approach for the analysis of small exploratory microarray experiments, Assumption adequacy averaging as a concept for developing more robust methods for differential gene expression analysis, Distribution modeling and simulation of gene expression data, The beta-binomial distribution for estimating the number of false rejections in microarray gene expression studies, Contaminated normal modeling with application to microarray data analysis, An empirical Bayes mixture method for effect size and false discovery rate estimation, Unsupervised empirical Bayesian multiple testing with external covariates, Incorporating the number of true null hypotheses to improve power in multiple testing: application to gene microarray data, A statistical method for estimating the proportion of differentially expressed genes, A Robust Method for Large-Scale Multiple Hypotheses Testing, Nonparametric Bayesian Estimation of Positive False Discovery Rates, Sample Size Calculations Based on Ranking and Selection in Microarray Experiments, A Tailored Multivariate Mixture Model for Detecting Proteins of Concordant Change Among Virulent Strains of Clostridium Perfringens, Interval estimation in a finite mixture model: Modeling \(P\)-values in multiple testing ap\-plications, Cluster analysis using multivariate normal mixture models to detect differential gene expression with microarray data, Efficient and robust density estimation using Bernstein type polynomials, Estimating the Proportion of True Null Hypotheses, with application to DNA Microarray Data, A semi-parametric approach for mixture models: application to local false discovery rate estimation, Nonparametric analysis of replicated microarray experiments, Flexible estimation of a semiparametric two-component mixture model with one parametric component, Randomization Tests for Small Samples: An Application for Genetic Expression Data, Chebyshev’s Inequality for Nonparametric Testing with Small N and α in Microarray Research

Cites Work