Estimating the Proportion of True Null Hypotheses, with application to DNA Microarray Data

DOI10.1111/j.1467-9868.2005.00515.xzbMath1095.62037OpenAlexW2065311047MaRDI QIDQ5473054

Mette Langaas, Egil Ferkingstad, Bo Henry Lindqvist

Publication date: 19 June 2006

Published in: Journal of the Royal Statistical Society Series B: Statistical Methodology (Search for Journal in Brave)

Full work available at URL: http://cds.cern.ch/record/639626

zbMATH Keywords

bioinformaticsGrenander estimator\(p\)-valuenonparametric maximum likelihood estimatormultiple testingdependent test statisticsdecreasing and convex density

Mathematics Subject Classification ID

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Uses Software

• R
• limma

Cites Work

• Unnamed Item
• A mixture model approach for the analysis of microarray gene expression data.
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• On the False Discovery Rate and Expected Type I Errors
• Strong Control, Conservative Point Estimation and Simultaneous Conservative Consistency of False Discovery Rates: A Unified Approach
• A Note on the Adaptive Control of False Discovery Rates
• A Simple Procedure for the Selection of Significant Effects
• A Direct Approach to False Discovery Rates
• Estimating the Proportion of True Null Hypotheses, with application to DNA Microarray Data
• Detecting differential gene expression with a semiparametric hierarchical mixture method

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