Control of the FWER in Multiple Testing Under Dependence

DOI10.1080/03610910902936281MaRDI QIDQ3645003zbMATH OpenOpenAlexFDO

Authors David Causeur, Maela Kloareg, Chloé Friguet

Publication date 16 November 2009

Published in Communications in Statistics: Theory and Methods (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/03610910902936281

zbMATH Keywords

factor analysisfamily-wise error rategene expression datamicroarray experimentsmultiple-hypothesis testingnon-discovery rate

Mathematics Subject Classification ID

Factor analysis and principal components; correspondence analysis (62H25) Linear regression; mixed models (62J05) Applications of statistics to biology and medical sciences; meta analysis (62P10) Paired and multiple comparisons; multiple testing (62J15)

Recommendations

• Evaluations of FWER-controlling methods in multiple hypothesis testing
• Generalized FWER control procedures for testing multiple hypotheses
• The control of the false discovery rate in multiple testing under dependency.
• FDR control in multiple testing under non-normality
• Evaluations of FDR-controlling procedures in multiple hypothesis testing
• A powerful FDR control procedure for multiple hypotheses
• Some Results on the Control of the False Discovery Rate under Dependence
• Multiple comparisons with control under stochastic ordering: controlling FDR
• Some remarks on the control of false discovery rate under dependence

Cites work

• Control of the mean number of false discoveries, Bonferroni and stability of multiple testing
• Correlation and Large-Scale Simultaneous Significance Testing
• Diverse correlation structures in gene expression data and their utility in improving statistical inference
• EM algorithms for ML factor analysis
• Estimating the Proportion of True Null Hypotheses, with application to DNA Microarray Data
• Multiple hypothesis testing in microarray experiments.
• Simultaneous confidence intervals for differential gene expressions
• Statistical significance for genomewide studies

Cited in

(10)

• Dependence aliasing and the control of family-wise error rate in multiple hypothesis testing
• FDR control in multiple testing under non-normality
• Empirical frequency band analysis of nonstationary time series
• A Bayesian approach to study design and analysis with type I error rate control for response variables of mixed types
• Covariate-adjusted multiple testing in genome-wide association studies via factorial hidden Markov models
• Uncertainty quantification for the family-wise error rate in multivariate copula models
• A factor model approach to multiple testing under dependence
• A general approach to account for dependence in large-scale multiple testing
• Farmtest: factor-adjusted robust multiple testing with approximate false discovery control
• Powerful multiple testing procedures derived from hyperrectangular confidence regions having a minimal volume

Describes a project that uses

Uses Software

• mvtnorm
• multtest
• FAMT

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