The control of the false discovery rate in multiple testing under dependency.

DOI10.1214/AOS/1013699998MaRDI QIDQ1848902zbMATHOpenAlexWikidataFDO

Authors Yoav Benjamini, Daniel Yekutieli

Publication date 14 November 2002

Published in The Annals of Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1214/aos/1013699998

zbMATH Keywords

FDRmultiple comparisons procedurespositive regression dependencyHochberg's procedurecomparisons with controldiscrete test statisticsMTP(2) densitiesmultiple endpoints many-to-one comparisonsSimes' equalityunidimensional latent variables

Mathematics Subject Classification ID

Measures of association (correlation, canonical correlation, etc.) (62H20) Paired and multiple comparisons; multiple testing (62J15) Applications of operator theory in probability theory and statistics (47N30)

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Cited in

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• Stepwise normal theory multiple test procedures controlling the false discovery rate
• On the false discovery proportion convergence under Gaussian equi-correlation
• Optimal rejection curves for exact false discovery rate control
• Detecting abrupt changes in a piecewise locally stationary time series
• False discovery rate control under Archimedean copula
• An optimal procedure for multiple hypotheses testing
• On stepwise control of directional errors under independence and some dependence
• Expected Power for the False Discovery Rate with Independence
• Some correlations in intersection-union tests and their relationship with complete power
• John W. Tukey's contributions to multiple comparisons
• Comments on: Optimization and data mining in medicine
• Simultaneous control of false positives and false negatives in multiple hypotheses testing
• False Discovery Control for Multiple Tests of Association Under General Dependence
• Testing the independence of maxima: from bivariate vectors to spatial extreme fields: asymptotic independence of extremes
• Simultaneous inference: when should hypothesis testing problems be combined?
• Deriving and comparing the distribution for the number of false positives in single step methods to control \(k\)-FWER
• Positive false discovery proportions: intrinsic bounds and adaptive control
• Separability tests for high-dimensional, low-sample size multivariate repeated measures data
• Sample size reassessment for a two-stage design controlling the false discovery rate
• On-line control of false discovery rates for multiple datastreams
• Distribution-free high-dimensional two-sample tests based on discriminating hyperplanes
• False discovery and false nondiscovery rates in single-step multiple testing procedures
• A clarifying comparison of methods for controlling the false discovery rate
• Modified Simes' critical values under positive dependence
• False discovery rates in somatic mutation studies of cancer
• FDR control with adaptive procedures and FDR monotonicity
• A Bayesian False Discovery Rate for Multiple Testing
• Asymptotics of Bonferroni for dependent normal test statistics
• Discovering significant patterns
• Step-up and step-down procedures controlling the number and proportion of false positives
• Inequalities for the false discovery rate (FDR) under dependence
• On optimality of the Benjamini-Hochberg procedure for the false discovery rate
• Incorporating the number of true null hypotheses to improve power in multiple testing: application to gene microarray data
• A generalized correlated binomial distribution with application in multiple testing problems
• Efficient computer experiment-based optimization through variable selection
• Fast Poisson noise removal by biorthogonal Haar domain hypothesis testing
• A more powerful step-up procedure for controlling the false discovery rate under independence
• Additive model selection
• Scan clustering: A false discovery approach
• FDR control for pairwise comparisons of normal means based on goodness of fit test
• A Scale‐space Approach for Detecting Non‐stationarities in Time Series
• Beyond panel unit root tests: using multiple testing to determine the nonstationarity properties of individual series in a panel
• A look at multiplicity through misclassification
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• Estimating inter-group interaction radius for point processes with nested spatial structures
• Hypothesis testing for Fourier based edge detection methods
• How the statistical validation of functional connectivity patterns can prevent erroneous definition of small-world properties of a brain connectivity network
• Two simple sufficient conditions for FDR control
• Balancing type one and two errors in multiple testing for differential expression of genes
• Evaluations of FDR-controlling procedures in multiple hypothesis testing
• Multiple testing via \(\mathrm{FDR}_L\) for large-scale imaging data
• A test for using the sum score to obtain a stochastic ordering of subjects
• Nonparametric significance testing and group variable selection
• Applying shrinkage variance estimators to the TOST test in high dimensional settings
• Asymptotic theory of dependent Bayesian multiple testing procedures under possible model misspecification
• Post-selection inference following aggregate level hypothesis testing in large-scale genomic data
• Structure-Specific Statistical Mapping of White Matter Tracts
• Cross-dimensional inference of dependent high-dimensional data
• A computationally efficient, exploratory approach to brain connectivity incorporating false discovery rate control, a priori knowledge, and group inference
• Redundancy as a graph-based index of frequency specific MEG functional connectivity
• Measuring network systemic risk contributions: a leave-one-out approach
• Statistical properties of gene-gene correlations in omics experiments
• Testing and support recovery of multiple high-dimensional covariance matrices with false discovery rate control
• A two-component copula with links to insurance
• The false discovery rate (FDR) of multiple tests in a class room lecture
• Environmental adaptation of proteins: regression models with simple physicochemical properties
• Parametric and Nonparametric FDR Estimation Revisited
• Multiple testing using the posterior probabilities of directional alternatives, with application to genomic studies
• Reproducibility of biomarker identifications from mass spectrometry proteomic data in cancer studies
• On Samuel's \(p\)-value model and the Simes test under dependence
• Cluster partitions and fitness landscapes of the Drosophila fly microbiome
• Non-marginal decisions: a novel Bayesian multiple testing procedure
• A new perspective on robust \(M\)-estimation: finite sample theory and applications to dependence-adjusted multiple testing
• Automated and distributed statistical analysis of economic agent-based models
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• Generate gene expression profile from high-throughput sequencing data
• Monotone false discovery rate
• Generalized estimating equations by considering additive terms for analyzing time-course gene sets data
• Mixed directional false discovery rate control in multiple pairwise comparisons using weighted \(p\)-values
• On empirical distribution function of high-dimensional Gaussian vector components with an application to multiple testing
• Adjusted regularization in latent graphical models: application to multiple-neuron spike count data
• A testing based approach to the discovery of differentially correlated variable sets
• False discovery rate control for effect modification in observational studies
• Simultaneous testing of multiple hypotheses using generalized \(p\)-values
• Local inference for functional data controlling the functional false discovery rate
• Separating Spike Count Correlation from Firing Rate Correlation
• On the Simes test under dependence
• Multiple testing for neuroimaging via hidden Markov random field
• Sequential tests of multiple hypotheses controlling false discovery and nondiscovery rates
• Post hoc confidence bounds on false positives using reference families
• A unified treatment of multiple testing with prior knowledge using the p-filter
• α-Investing: a Procedure for Sequential Control of Expected False Discoveries
• Detecting and testing altered brain connectivity networks with \(k\)-partite network topology
• A two-sample test for the equality of univariate marginal distributions for high-dimensional data
• Quality analysis in acyclic production networks
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• Online rules for control of false discovery rate and false discovery exceedance
• Automated selection of \(r\) for the \(r\) largest order statistics approach with adjustment for sequential testing
• Analyzing factorial designed microarray experiments
• Simultaneous high-probability bounds on the false discovery proportion in structured, regression and online settings

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