Exploring the Information in p‐Values for the Analysis and Planning of Multiple‐Test Experiments

DOI10.1111/j.1541-0420.2006.00704.xzbMath1152.62087OpenAlexW2092327318WikidataQ50928988 ScholiaQ50928988MaRDI QIDQ5459592

J. T. Gene Hwang, Dan Nettleton, David Ruppert

Publication date: 29 April 2008

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1111/j.1541-0420.2006.00704.x

zbMATH Keywords

splinesinverse problemsample sizepowerfalse discovery ratemicroarraypenaltysimultaneous testsexpected discovery rate

Mathematics Subject Classification ID

Density estimation (62G07) Applications of statistics to biology and medical sciences; meta analysis (62P10) Parametric hypothesis testing (62F03) Quadratic programming (90C20) Estimation in survival analysis and censored data (62N02) Testing in survival analysis and censored data (62N03)

Related Items (14)

Deconvolution estimation of mixture distributions with boundaries ⋮ Semiparametric regression during 2003--2007 ⋮ Bayesian adaptive B-spline estimation in proportional hazards frailty models ⋮ Estimating the proportion of true null hypotheses using the pattern of observedp-values ⋮ Linear Score Tests for Variance Components in Linear Mixed Models and Applications to Genetic Association Studies ⋮ A multiple testing protocol for exploratory data analysis and the local misclassification rate ⋮ A Hierarchical Semiparametric Model for Incorporating Intergene Information for Analysis of Genomic Data ⋮ Improved Estimation of the Noncentrality Parameter Distribution from a Large Number of t‐Statistics, with Applications to False Discovery Rate Estimation in Microarray Data Analysis ⋮ Multiple Testing of Composite Null Hypotheses in Heteroscedastic Models ⋮ Estimation of False Discovery Rate Using Sequential Permutation p‐Values ⋮ A cross-validation based estimation of the proportion of true null hypotheses ⋮ RandomisedP-values and nonparametric procedures in multiple testing ⋮ General power and sample size calculations for high-dimensional genomic data ⋮ Least squares sieve estimation of mixture distributions with boundary effects

Uses Software

• SemiPar

Cites Work

• Unnamed Item
• Estimating the proportion of false null hypotheses among a large number of independently tested hypotheses
• On the optimal rates of convergence for nonparametric deconvolution problems
• A stochastic process approach to false discovery control.
• A variation on the minimum chi-square test
• Optimal Rates of Convergence for Deconvolving a Density
• An Algorithm for Computing the Nonparametric MLE of a Mixing Distribution
• A Direct Approach to False Discovery Rates
• Power and sample size estimation in high dimensional biology
• Statistical significance for genomewide studies
• Estimating the Proportion of True Null Hypotheses, with application to DNA Microarray Data
• Large-Scale Simultaneous Hypothesis Testing

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