A physical model for dementia

DOI10.1016/J.PHYSA.2016.12.086MaRDI QIDQ1620512zbMATH OpenOpenAlexWikidataFDO

Authors O. Sotolongo-Costa, L. M. Gaggero-Sager, J. T. Becker, F. Maestu, O. Sotolongo-Grau

Publication date 13 November 2018

Published in Physica A (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1410.1025

zbMATH Keywords

catastrophe theorycuspdementiastochastic process

Mathematics Subject Classification ID

General biostatistics (92B15) Medical applications (general) (92C50)

Abstract: Aging associated brain decline often result in some kind of dementia. Even when this is a complex brain disorder a physical model can be used in order to describe its general behavior. This model is based in first principles. A probabilistic model for the development of dementia is obtained and fitted to some experimental data obtained from the Alzheimer's Disease Neuroimaging Initiative. It is explained how dementia appears as a consequence of aging and why it is irreversible.

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Cites work

• Alzheimer's disease: analysis of a mathematical model incorporating the role of prions
• scientific article; zbMATH DE number 54061 (Why is no real title available?)

Cited in

(2)

• Multi-state Model for Dementia, Institutionalization, and Death
• Brain game design for elderly

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• cusp

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