Bistability in a model of mesoderm and anterior mesendoderm specification in \textit{Xenopus laevis}

DOI10.1016/J.JTBI.2009.05.016MaRDI QIDQ1625833zbMATH OpenOpenAlexWikidataFDO

Authors Alistair M. Middleton, J. R. King, Matthew Loose

Publication date 26 November 2018

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2009.05.016

zbMATH Keywords

cell differentiationembryo developmentgene network

Mathematics Subject Classification ID

Developmental biology, pattern formation (92C15) Biochemistry, molecular biology (92C40)

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Cites work

• Combining cytokine signalling with T-bet and GATA-3 regulation in Th1 and Th2 differentiation: a model for cellular decision-making
• Simulating, Analyzing, and Animating Dynamical Systems
• Towards an understanding of lineage specification in hematopoietic stem cells: a mathematical model for the interaction of transcription factors GATA-1 and PU.1

Cited in

(7)

• Signalling-modulated gene regulatory networks in early mammalian development
• A simple model of two interacting signaling pathways in embryonic Xenopus laevis
• Wave pinning and spatial patterning in a mathematical model of antivin/lefty-nodal signalling
• Quantitative analysis of cell arrangement indicates early differentiation of the neural region during \textit{Xenopus} gastrulation
• Two different network topologies yield bistability in models of mesoderm and anterior mesendoderm specification in amphibians
• Interaction of the IP\(_{3}\)-Ca\(^{2+}\) and MAPK signaling systems in the \textit{Xenopus} blastomere: A possible frequency encoding mechanism for the control of the \textit{Xbra} gene expression
• Multicellular mathematical modelling of mesendoderm formation in amphibians

Describes a project that uses

Uses Software

• XPPAUT

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