Variability of the distribution of differentiation pathway choices regulated by a multipotent delayed stochastic switch

DOI10.1016/J.JTBI.2009.05.025MaRDI QIDQ1625836zbMATH OpenOpenAlexWikidataFDO

Authors André Silva Ribeiro, Xiaofeng Dai, O. Yli-Harja

Publication date 26 November 2018

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2009.05.025

zbMATH Keywords

cell lineagegene regulatory networkstochastictoggle switch

Mathematics Subject Classification ID

Cell biology (92C37) Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10)

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Cites work

• Boolean dynamics with random couplings
• Noisy attractors and ergodic sets in models of gene regulatory networks
• Studying genetic regulatory networks at the molecular level: delayed reaction stochastic models

Cited in

(5)

• A model of sequential branching in hierarchical cell fate determination
• Tuning cell differentiation patterns and single cell dynamics by regulating proteins' functionalities in a toggle switch
• Cell-type switches induced by stochastic histone modification inheritance
• Generalized, switch-like competitive heterodimerization networks
• Stochastic and delayed stochastic models of gene expression and regulation

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Uses Software

• SGN Sim

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