Long negative feedback loop enhances period tunability of biological oscillators

DOI10.1016/j.jtbi.2017.12.014zbMath1400.92034OpenAlexW2771707358WikidataQ49663701 ScholiaQ49663701MaRDI QIDQ1648928

Hiroyuki Kurata, Kazuhiro Maeda

Publication date: 5 July 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2017.12.014

zbMATH Keywords

sensitivitysimulationsynthetic biologysystems biologyfeedback loopcircadian rhythmrepressilatortemperature compensation

Mathematics Subject Classification ID

Systems biology, networks (92C42) Biological rhythms and synchronization (92B25)

Uses Software

• SUNDIALS

Cites Work

• SUNDIALS
• Modeling synthetic gene oscillators
• The secant condition for instability in biochemical feedback control. I: The role of cooperativity and saturability
• Quasi-multiparameter sensitivity measure for robustness analysis of complex biochemical networks
• Mathematical physiology. I: Cellular physiology
• Designer gene networks: Towards fundamental cellular control

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