Inferring intracellular signal transduction circuitry from molecular perturbation experiments

DOI10.1007/S11538-017-0270-9zbMATH Open1394.92034OpenAlexW2951331687WikidataQ38705548 ScholiaQ38705548MaRDI QIDQ1649006FDOQ1649006

Authors: Michelle L. Wynn, Megan Egbert, Nikita Consul, Jungsoo Chang, Zhi-Fen Wu, Sofia D. Meravjer, Santiago Schnell 

Publication date: 5 July 2018

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc5660674

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zbMATH Keywords

breast cancernetwork inferenceBoolean modelscellular signaling

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42) Cell biology (92C37)

Cites Work

• Title not available (Why is that?)
• An introduction to genetic algorithms.
• Robustness and fragility of Boolean models for genetic regulatory networks
• The topology of the regulatory interactions predicts the expression pattern of the segment polarity genes in \textit{Drosophila melanogaster}

Cited In (3)

• ExPlain\(^{\text{TM}}\)-WAX: causal analysis of gene batteries and identification of key nodes in signal transduction networks
• Mathematical oncology
• A linear programming model based on network flow for pathway inference

Uses Software

• booleannet
• REVEAL

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