Optimal experimental designs for estimating the drug combination index in toxicology

DOI10.1016/j.csda.2017.08.006zbMath1437.62300OpenAlexW2751888887MaRDI QIDQ1662053

Tim Holland-Letz, Annette Kopp-Schneider

Publication date: 17 August 2018

Published in: Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.csda.2017.08.006

zbMATH Keywords

nonlinear regressiontoxicology\(c\)-optimal designmultiplicative algorithmsdose-response studiescombination index

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) General nonlinear regression (62J02)

Related Items (1)

Compromise design for combination experiment of two drugs

Cites Work

• Unnamed Item
• Unnamed Item
• Unnamed Item
• Unnamed Item
• Monotonic convergence of a general algorithm for computing optimal designs
• Optimal Bayesian design applied to logistic regression experiments
• General equivalence theory for optimum designs (approximate theory)
• Experimental designs for drug combination studies
• On the regularization of singular c-optimal designs
• Optimal Design of Experiments
• On the combination of c‐ and D‐optimal designs: General approaches and applications in dose–response studies
• Locally Optimal Designs for Estimating Parameters

This page was built for publication: Optimal experimental designs for estimating the drug combination index in toxicology