Optimal experimental designs for estimating the drug combination index in toxicology
DOI10.1016/J.CSDA.2017.08.006zbMATH Open1437.62300OpenAlexW2751888887MaRDI QIDQ1662053FDOQ1662053
Authors: Tim Holland-Letz, Annette Kopp-Schneider 
Publication date: 17 August 2018
Published in: Computational Statistics and Data Analysis (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1016/j.csda.2017.08.006
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nonlinear regressiontoxicology\(c\)-optimal designmultiplicative algorithmsdose-response studiescombination index
General nonlinear regression (62J02) Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05)
Cites Work
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- General equivalence theory for optimum designs (approximate theory)
- Optimum experimental designs, with SAS
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- Monotonic convergence of a general algorithm for computing optimal designs
- Optimal Bayesian design applied to logistic regression experiments
- Locally Optimal Designs for Estimating Parameters
- Optimal Design of Experiments
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- On the regularization of singular c-optimal designs
- Experimental designs for drug combination studies
- On the combination of c‐ and D‐optimal designs: General approaches and applications in dose–response studies
Cited In (8)
- Optimal designs for discriminating between dose-response models in toxicology studies
- Compromise design for combination experiment of two drugs
- Utility-Based Optimization of Combination Therapy Using Ordinal Toxicity and Efficacy in Phase I/II Trials
- Optimal adaptive designs for acute oral toxicity assessment
- Optimum experimental designs for comparative bioavailability studies
- Optimal 3×3 factorial and 3-ray designs for drug interaction experiments with dichotomous responses
- Optimal designs for dose-finding experiments in toxicity studies
- A Generalized Response Surface Model with Varying Relative Potency for Assessing Drug Interaction
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