A multi-stage representation of cell proliferation as a Markov process

DOI10.1007/s11538-017-0356-4zbMath1380.92017arXiv1705.09718OpenAlexW2617921759WikidataQ47113485 ScholiaQ47113485MaRDI QIDQ1696398

Christian A. Yates, Richard L. Mort, Matthew J. Ford

Publication date: 14 February 2018

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1705.09718

zbMATH Keywords

stochastic simulationcell cycleGillespie algorithmMarkovian representationexponentially modified Erlang

Mathematics Subject Classification ID

Cell biology (92C37) Applications of continuous-time Markov processes on discrete state spaces (60J28)

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Uses Software

• Fiji
• ImageJ

Cites Work

• Unnamed Item
• Demographic modeling of transient amplifying cell population growth
• Exponentially modified Gaussian (EMG) relevance to distributions related to cell proliferation and differentiation
• A general mathematical framework to model generation structure in a population of asynchronously dividing cells
• Derivation and experimental comparison of cell-division probability densities
• Estimating the Generation-Time Distribution of an Age-Dependent Branching Process
• ON THE ROLE OF VARIABLE GENERATION TIME IN THE DEVELOPMENT OF A STOCHASTIC BIRTH PROCESS
• Markoff Chains--Denumerable Case