Low-resolution simulations of vesicle suspensions in 2D

DOI10.1016/J.JCP.2017.12.023zbMATH Open1381.76373arXiv1702.04709OpenAlexW2588122669MaRDI QIDQ1699458FDOQ1699458

Authors: Gökberk Kabacaoğlu, George Biros, Bryan D. Quaife 

Publication date: 23 February 2018

Published in: Journal of Computational Physics (Search for Journal in Brave)

Abstract: Vesicle suspensions appear in many biological and industrial applications. These suspensions are characterized by rich and complex dynamics of vesicles due to their interaction with the bulk fluid, and their large deformations and nonlinear elastic properties. Many existing state-of-the-art numerical schemes can resolve such complex vesicle flows. However, even when using provably optimal algorithms, these simulations can be computationally expensive, especially for suspensions with a large number of vesicles. In this paper, we investigate the effect of a number of algorithmic empirical fixes in an attempt to make low-resolution simulations more stable and more predictive. Based on our empirical studies for a number of flow configurations, we propose a scheme that attempts to integrate these fixes in a systematic way. This low-resolution scheme is an extension of our previous work Quaife and Biros (2014) and Quaife and Biros (2016). Our low-resolution correction algorithms (LRCA) include anti-aliasing and membrane reparametrization for avoiding spurious oscillations in vesicles' membranes, adaptive time stepping and a repulsion force for handling vesicle collisions and, correction of vesicles' area and arc-length for maintaining physical vesicle shapes. We perform a systematic error analysis by comparing the low-resolution simulations of dilute and dense suspensions with their high-fidelity, fully resolved, counterparts. We observe that the LRCA enables both efficient and statistically accurate low-resolution simulations of vesicle suspensions, while it can be 10x to 100x faster.

Full work available at URL: https://arxiv.org/abs/1702.04709

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zbMATH Keywords

boundary integral equationsStokes flowred blood cellsparticulate flowssuspensionsvesicle suspensions

Mathematics Subject Classification ID

Stokes and related (Oseen, etc.) flows (76D07) Suspensions (76T20) Physiological flows (76Z05) Boundary element methods applied to problems in fluid mechanics (76M15)

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Cited In (8)

• Adaptive time stepping for vesicle suspensions
• Mixing in a sheared particulate suspension
• Sorting same-size red blood cells in deep deterministic lateral displacement devices
• A boundary-integral framework to simulate viscous erosion of a porous medium
• Low-resolution simulations of vesicle suspensions in 2D
• Modelling solute transport in the brain microcirculation: is it really well mixed inside the blood vessels?
• Two-dimensional hydrodynamics of a Janus particle vesicle
• Dynamic simulation of locally inextensible vesicles suspended in an arbitrary two-dimensional domain, a boundary integral method

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