Determining the role of inflammation in the selection of JAK2 mutant cells in myeloproliferative neoplasms

DOI10.1016/J.JTBI.2017.05.012zbMath1381.92053OpenAlexW2951039728WikidataQ45966435 ScholiaQ45966435MaRDI QIDQ1701585

Natalia L. Komarova, Angela G. Fleischman, Jie Zhang, Dominik Wodarz

Publication date: 27 February 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc5689470

zbMATH Keywords

evolutionary dynamicshematopoietic diseaseODE modelingaxiomatic modeling

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40)

Related Items (3)

Global dynamics of healthy and cancer cells competing in the hematopoietic system ⋮ Bridging blood cancers and inflammation: the reduced cancitis model ⋮ Mathematical analysis of the cancitis model and the role of inflammation in blood cancer progression

Cites Work

• Mechanistic simulations of inflammation: current state and future prospects
• A systems-theoretical framework for health and disease: inflammation and preconditioning from an abstract modeling point of view
• Mathematical Modeling of Leukemogenesis and Cancer Stem Cell Dynamics
• A mathematical framework to determine the temporal sequence of somatic genetic events in cancer

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