A mathematical framework to determine the temporal sequence of somatic genetic events in cancer

DOI10.1073/PNAS.1009117107zbMATH Open1256.92023OpenAlexW2101354849WikidataQ34200279 ScholiaQ34200279MaRDI QIDQ4907447FDOQ4907447

Authors: Camille Stephan-Otto Attolini, Yu-Kang Cheng, Rameen Beroukhim, Gad Getz, Omar Abdel-Wahab, Ross Levine, Ingo K. Mellinghoff, Franziska Michor 

Publication date: 2 February 2013

Published in: Proceedings of the National Academy of Sciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1073/pnas.1009117107

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zbMATH Keywords

tumorigenesistemporal sequence of mutations

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10)

Cited In (4)

• Measuring evolutionary cancer dynamics from genome sequencing, one patient at a time
• Mathematical model of colorectal cancer initiation
• Fixation times in differentiation and evolution in the presence of bottlenecks, deserts, and oases
• Determining the role of inflammation in the selection of JAK2 mutant cells in myeloproliferative neoplasms

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