Measuring evolutionary cancer dynamics from genome sequencing, one patient at a time

DOI10.1515/SAGMB-2020-0075MaRDI QIDQ830656zbMATH OpenOpenAlexFDO

Authors Giulio Caravagna

Publication date 7 May 2021

Published in Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1515/sagmb-2020-0075

zbMATH Keywords

clonal evolutionbulk genome sequencingsubclonal deconvolution

Mathematics Subject Classification ID

Genetics and epigenetics (92D10) Problems related to evolution (92D15) Protein sequences, DNA sequences (92D20) Pathology, pathophysiology (92C32)

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Cites work

• scientific article; zbMATH DE number 46731 (Why is no real title available?)
• scientific article; zbMATH DE number 1761225 (Why is no real title available?)
• Conjunctive Bayesian networks
• Evolutionary dynamics. Exploring the equations of life.
• Exact solution of a two-type branching process: clone size distribution in cell division kinetics
• Large population solution of the stochastic Luria-Delbrück evolution model
• Line-of-descent and genealogical processes, and their applications in population genetics models
• Pattern recognition and machine learning.
• Scaling solution in the large population limit of the general asymmetric stochastic Luria-Delbrück evolution process

Cited in

(3)

• Quantifying selection in evolving populations using time-resolved genetic data
• On statistical modeling of sequencing noise in high depth data to assess tumor evolution
• scientific article; zbMATH DE number 5852865 (Why is no real title available?)

Describes a project that uses

Uses Software

• PRMLT
• TEMULATOR
• GitHub
• SciClone
• PyClone
• PhyloWGS

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