How to choose biomarkers in view of parameter estimation

DOI10.1016/J.MBS.2018.06.003MaRDI QIDQ1711958zbMATH OpenOpenAlexWikidataFDO

Authors J.-F. Gerbeau, Damiano Lombardi, Eliott Tixier

Publication date 18 January 2019

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://hal.inria.fr/hal-01811158/file/bionum_HAL.pdf

zbMATH Keywords

electrophysiologyfeature selectionhemodynamicsinverse problemssparse optimization

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) General biostatistics (92B15) Biochemistry, molecular biology (92C40) Medical applications (general) (92C50)

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Cites work

• 10.1162/153244303322753616
• A sensitivity matrix based methodology for inverse problem formulation
• Active subspaces. Emerging ideas for dimension reduction in parameter studies
• Adaptive restart for accelerated gradient schemes
• Kernel methods and haplotypes used in selection of sparse DNA markers for protein yield in dairy cattle
• Kinetic scheme for arterial and venous blood flow, and application to partial hepatectomy modeling
• Nonstationary inverse problems and state estimation
• Parametric uncertainty and global sensitivity analysis in a model of the carotid bifurcation: identification and ranking of most sensitive model parameters
• Structural correlation method for model reduction and practical estimation of patient specific parameters illustrated on heart rate regulation
• Study of a perturbation in the coding periodicity
• The Collinearity Problem in Linear Regression. The Partial Least Squares (PLS) Approach to Generalized Inverses
• The dimensional reduction method for identification of parameters that trade-off due to similar model roles

Cited in

(3)

• Sample size determination for high dimensional parameter estimation with application to biomarker identification
• Measuring and visualizing the stability of biomarker selection techniques
• Alzheimer biomarkers esteem by sampling Kantorovich algorithm

Describes a project that uses

Uses Software

• BOBYQA

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