Regulation of tumour intracellular pH: a mathematical model examining the interplay between H\(^+\) and lactate

DOI10.1016/J.JTBI.2013.01.007zbMath1406.92141OpenAlexW1972702647WikidataQ51274966 ScholiaQ51274966MaRDI QIDQ1715210

Maymona Al-Husari, Steven D. Webb

Publication date: 4 February 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2013.01.007

zbMATH Keywords

modellinglactate/H\(^+\) symporterNa\(^+\)/H\(^+\) antiporterpH gradienttumour microenvironment

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical applications (general) (92C50) Cell biology (92C37)

Related Items (1)

A cellular automaton model examining the effects of oxygen, hydrogen ions and lactate on early tumour growth

Uses Software

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Cites Work

• Mathematical model of pulsed immunotherapy for superficial bladder cancer
• Necrotic core in EMT6/Ro tumour spheroids: is it caused by an ATP deficit?
• Mathematical modelling of cancer cell invasion of tissue: local and non-local models and the effect of adhesion
• The role of acidity in solid tumour growth and invasion

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