Generalizing a mathematical model of prion aggregation allows strain coexistence and co-stability by including a novel misfolded species

DOI10.1007/s00285-018-1280-4zbMath1411.92234OpenAlexW2886609209WikidataQ64989972 ScholiaQ64989972MaRDI QIDQ1738034

Suzanne S. Sindi, Paul Lemarre, Laurent Pujo-Menjouet

Publication date: 29 March 2019

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-018-1280-4

zbMATH Keywords

coexistenceprotein aggregationnucleated polymerizationprionsprotein misfoldingstrainssubunits

Mathematics Subject Classification ID

Stability of solutions to ordinary differential equations (34D20) Protein sequences, DNA sequences (92D20)

Related Items (1)

Neuron Scale Modeling of Prion Production with the Unfolded Protein Response

Cites Work

• Unnamed Item
• A mathematical model of the dynamics of prion aggregates with chaperone-mediated fragmentation
• Analysis of a model for the dynamics of prions. II
• A mathematical analysis of the dynamics of prion proliferation
• A study in nucleated polymerization models of protein aggregation
• Scaling limit of a discrete prion dynamics model
• Analysis of a model for the dynamics of prions
• A Primer on Mathematical Models in Biology
• Prion dynamics with size dependency–strain phenomena

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