Towards dynamic PET reconstruction under flow conditions: parameter identification in a PDE model

DOI10.1515/JIIP-2015-0016zbMATH Open1388.35102arXiv1411.5143OpenAlexW2964259327MaRDI QIDQ1746495FDOQ1746495

Authors: L. Reips, Martin Burger, Ralf Engbers 

Publication date: 25 April 2018

Published in: Journal of Inverse and Ill-posed Problems (Search for Journal in Brave)

Abstract: The aim of this paper is to discuss potential advances in PET kinetic models and direct reconstruction of kinetic parameters. As a prominent example we focus on a typical task in perfusion imaging and derive a system of transport-reaction-diffusion equations, which is able to include macroscopic flow properties in addition to the usual exchange between arteries, veins, and tissues. For this system we propose an inverse problem of estimating all relevant parameters from PET data. We interpret the parameter identification as a nonlinear inverse problem, for which we formulate and analyze variational regularization approaches. For the numerical solution we employ gradient-based methods and appropriate splitting methods, which are used to investigate some test cases.

Full work available at URL: https://arxiv.org/abs/1411.5143

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zbMATH Keywords

transportparameter identificationinverse problemsdiffusionimage processingforward-backward splittingreactiondynamic PET

Mathematics Subject Classification ID

PDEs in connection with fluid mechanics (35Q35) Reaction-diffusion equations (35K57) Inverse problems for PDEs (35R30)

Cites Work

• Statistical and computational inverse problems.
• Mathematical methods in image reconstruction
• (Nonlocal) total variation in medical imaging
• Optimization with PDE Constraints
• Title not available (Why is that?)
• Primal and dual Bregman methods with application to optical nanoscopy
• Title not available (Why is that?)
• Title not available (Why is that?)
• Title not available (Why is that?)
• The finite volume Scharfetter-Gummel method for steady convection diffusion equations
• Convergence rates in expectation for Tikhonov-type regularization of inverse problems with Poisson data
• EM-TV Methods for Inverse Problems with Poisson Noise
• A Statistical Model for Positron Emission Tomography
• Title not available (Why is that?)
• Parameter identification in medical imaging

Cited In (6)

• Camouflaged Deconvolution With Application to Blood Curve Modeling in FDG PET Studies
• Parameter identification in medical imaging
• A Bayesian model for dynamic mass reconstruction from PET listmode data
• Kinetic modeling in the context of cerebral blood flow quantification by H\(_2^{15}\)O positron emission tomography: the meaning of the permeability coefficient in Renkin-Crone's model revisited at capillary scale
• Simultaneous estimation of tracer kinetic model parameters using analytical and inverse approaches with a hybrid method
• Under-relaxed quasi-Newton acceleration for an inverse fixed-point problem coming from positron emission tomography

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