Multistage nonparametric tests for treatment comparisons in clinical trials with multiple primary endpoints

DOI10.4310/SII.2016.V9.N3.A8MaRDI QIDQ1747595zbMATH OpenOpenAlexFDO

Authors Ming T. Tan, Peng Huang

Publication date 8 May 2018

Published in Statistics and Its Interface (Search for Journal in Brave)

Full work available at URL https://doi.org/10.4310/sii.2016.v9.n3.a8

zbMATH Keywords

adaptive group sequential testBehrens-Fisher problemBrownian motionrank-based test

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Hypothesis testing in multivariate analysis (62H15) Sequential statistical design (62L05) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(4)

• Multiple comparisons of treatments with stable multivariate tests in a two-stage adaptive design, including a test for non-inferiority
• A nonparametric test for the evaluation of group sequential clinical trials with covariate information
• Directional Tests for the Analysis of Clinical Trials with Multiple Endpoints Allowing for Incomplete Data
• Highly robust causal semiparametric U-statistic with applications in biomedical studies

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