Impact of plasma-protein binding on receptor occupancy: an analytical description

DOI10.1016/J.JTBI.2008.09.014MaRDI QIDQ1798741zbMATH OpenOpenAlexWikidataFDO

Authors Lambertus A. Peletier, Neil Benson, Piet H. van der Graaf

Publication date 23 October 2018

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2008.09.014

zbMATH Keywords

analytical descriptionsmodelling complex systems behavioursplasma-protein bindingreceptor occupancytime scales

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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Cited in

(10)

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• Equilibrium binding of multivalent ligands to cells: Effects of cell and receptor density
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• Monotonicity of interleukin-1 receptor-ligand binding with respect to antagonist in the presence of decoy receptor
• Antagonist binding in the rat muscarinic receptor: A study by docking and X-ray crystallogra\-phy
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