Extending the multiple indicator dilution method to include slow intracellular diffusion

DOI10.1016/0025-5564(93)90002-RzbMATH Open0767.92009WikidataQ46301266 ScholiaQ46301266MaRDI QIDQ1802920FDOQ1802920

Authors Bruce A. Luxon, Richard A. Weisiger

Publication date 29 June 1993

Published in Mathematical Biosciences (Search for Journal in Brave)

zbMATH Keywords

transport processesLaplace transformationsimulation analysiscytoplasmic concentration gradientsestimation of the rate of intracellular transport of amphipathic moleculesMID methodmultiple indicator dilution methodoutflow curvesslow intracellular diffusiontransmembrane and excretion processes

Mathematics Subject Classification ID

Probabilistic models, generic numerical methods in probability and statistics (65C20) Physiology (general) (92C30) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Physiological flow (92C35)

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Cites work

• scientific article; zbMATH DE number 3119876 (Why is no real title available?)
• Algorithm 619: automatic numerical inversion of the Laplace transform [D5]
• An effective-diffusivity model of pulmonary capillary exchange: General theory, limiting cases, and sensitivity analysis
• Dud, A Derivative-Free Algorithm for Nonlinear Least Squares
• The physiological role of myoglobin: More than a problem in reaction- diffusion kinetics

Cited in

(4)

• scientific article; zbMATH DE number 3920270 (Why is no real title available?)
• Extension of the theory of the multiple-indicator dilution technique to metabolic systems with an arbitrary number of rate constants
• On the validity of the dispersion model of hepatic drug elimination when intravascular transit time densities are long-tailed
• Importance of Taylor dispersion in pharmacokinetic and multiple indicator dilution modelling

Describes a project that uses

Uses Software

• Algorithm 619

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