Global dynamics of an age-structured model with relapse

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Publication:1987155





The authors provide in this paper a complete mathematical analysis of a general class of SIRI age infection structured models, where the \(R\) class is replaced by a \(q\) class, \(q\) standing for quarantine in this work. Using classical techniques, the authors compute a basic reproduction number \(R_0\) and show that the disease dies out when \(R_0<1\) and persists if \(R_0>1\). Some Lyapunov suitable functions are derived to prove global stability for the disease free equilibrium (DFE) when \(R_0<1\) and for the endemic equilibrium (EE) when \(R_0>1\). Using numerical results, the authors show that the non-homogeneous infectivity combined with the feedback to the infectiousness class of a part of the quarantine population modifies drastically the behavior of the epidemic.



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