Early and late stage profiles for a chemotaxis model with density-dependent jump probability

DOI10.3934/MBE.2018062zbMATH Open1416.92030arXiv1711.08114OpenAlexW2892228557WikidataQ93004012 ScholiaQ93004012MaRDI QIDQ2000768FDOQ2000768

Jingxue Yin, Ming Mei, Shanming Ji, Tianyuan Xu, Chunhua Jin

Publication date: 28 June 2019

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Abstract: In this paper, we derive a new chemotaxis model with degenerate diffusion and density-dependent chemotactic sensitivity, and we provide a more realistic description of cell migration process for its early and late stages. Different from the existing studies focusing on the case of non-degenerate diffusion, the new model with degenerate diffusion causes us some essential difficulty on the boundedness estimates and the propagation behavior of its compact support. In the presence of logistic damping, for the early stage before tumour cells spread to the whole body, we first estimate the expanding speed of tumour region as $$ for $$. Then, for the late stage of cell migration, we further prove that the asymptotic profile of the original system is just its corresponding steady state. The global convergence of the original weak solution to the steady state with exponential rate $O(e^{-ct})$ for some $c>0$ is also obtained.

Full work available at URL: https://arxiv.org/abs/1711.08114

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zbMATH Keywords

degenerate diffusionchemotaxis modelfinite speed propagationdensity-dependent jump probabilityporous media diffusiontumour invasions models

Mathematics Subject Classification ID

Reaction-diffusion equations (35K57) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Cell movement (chemotaxis, etc.) (92C17)

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Cited In (6)

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• Existence of weak solutions to an anisotropic parabolic–parabolic chemotaxis system
• A reducing mechanism on wave speed for chemotaxis systems with degenerate diffusion
• On a chemotaxis model with degenerate diffusion: initial shrinking, eventual smoothness and expanding
• Dirichlet problem for the Nicholson's blowflies equation with density-dependent diffusion
• Traveling Waves in Degenerate Diffusion Equations

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