Estimation of the HIV-1 backward mutation rate from transmitted drug-resistant strains

DOI10.1016/J.TPB.2016.08.001zbMATH Open1367.92076OpenAlexW2507502024WikidataQ37447287 ScholiaQ37447287MaRDI QIDQ2011533FDOQ2011533

Authors: J. Y. T. Mugisha, John M. Kitayimbwa, Roberto A. Saenz 

Publication date: 4 August 2017

Published in: Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.tpb.2016.08.001

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zbMATH Keywords

HIV-1within-host modelvirus mutationsKaplan-Meier estimatesbackward mutation rate

Mathematics Subject Classification ID

Epidemiology (92D30) Genetics and epigenetics (92D10) Problems related to evolution (92D15)

Cites Work

• Dynamics of HIV infection of CD4\(^ +\) T cells
• Emergence of HIV-1 drug resistance during antiretroviral treatment
• Monte Carlo estimates of natural variation in HIV infection
• The role of backward mutations on the within-host dynamics of HIV-1
• Production of resistant HIV mutants during antiretroviral therapy

Cited In (3)

• Dynamic analysis of conversion from a drug-sensitivity strain to a drug-resistant strain
• Characterization of differential susceptibility and differential infectivity epidemic models
• Combining Cross‐Sectional and Prospective Data Methods to Improve Transition Parameter Estimation for Characterizing the Accumulation of HIV‐1 Drug Resistance Mutations

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