Dynamics of HIV infection of CD4^ + T cells

DOI10.1016/0025-5564(93)90043-AzbMATH Open0796.92016WikidataQ52400530 ScholiaQ52400530MaRDI QIDQ1802910FDOQ1802910

Authors: Alan S. Perelson, Denise E. Kirschner, Rob J. De Boer

Publication date: 29 June 1993

Published in: Mathematical Biosciences (Search for Journal in Brave)

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differential equations immune response numerical analysis dynamics of HIV infection T-cell depletion T-cell replenishment

Mathematics Subject Classification ID

Medical applications (general) (92C50) Medical epidemiology (92C60)

Cites Work

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A deterministic model for gonorrhea in a nonhomogeneous population
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Mathematical biology of HIV infections: Antigenic variation and diversity threshold
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Cited In (only showing first 100 items - show all)

Resistance to protease inhibitors in a model of HIV-1 infection with impulsive drug effects
Mutation and control of the human immunodeficiency virus
Nonlinear dynamics and chaos in a fractional-order HIV model
Stability analysis of within-host parasite models with delays
Modelling two different therapy strategies for drug T-20 on HIV-1 patients
Some state space models of HIV pathogenesis under treatment by anti-viral drugs in HIV-infected individuals
Modeling the role of acquired immune response and antiretroviral therapy in the dynamics of HIV infection
Mathematical modeling of HIV-1 infection and drug therapy
Solving a system of fractional partial differential equations arising in the model of HIV infection of \(\mathrm{CD4}^{+}\) cells and attractor one-dimensional Keller-Segel equations
Stability analysis for delayed viral infection model with multitarget cells and general incidence rate
Epidemic dynamics and host immune response: a nested approach
The T cells in an ageing virtual mouse
Global asymptotic stability for the disease free equilibrium for epidemiological models
A dynamical model of human immune response to influenza A virus infection
The global dynamics of a model about HIV-1 infection in vivo
Multiscale modelling of cancer response to oncolytic viral therapy
A time delay model about AIDS-related cancer: equilibria, cycles and chaotic behavior
Viral diffusion and cell-to-cell transmission: mathematical analysis and simulation study
Mathematical Models of the Complete Course of HIV Infection and AIDS
A mathematical model for chronic myelogenous leukemia (CML) and T cell interaction
A mathematical model of HIV infection: Simulating T4, T8 macrophages, antibody, and virus via specific anti-HIV response in the presence of adaptation and tropism
A Comparison Study of Models and Fitting Procedures for Biphasic Viral Dynamics in HIV‐1 Infected Patients Treated with Antiviral Therapies
Impulsive control of single-input nonlinear systems with application to HIV dynamics
A mathematical model for HIV treatment with time-varying antiretroviral therapy
An HIV model with age-structured latently infected cells
Threshold dynamics for an HIV model in periodic environments
An accurate two-phase approximate solution to an acute viral infection model
Backward bifurcation in a mathematical model for HIV infection \textit{in vivo} with anti-retroviral treatment
Global dynamics of a PDE in-host viral model
First passage time to detection in stochastic population dynamical models for HIV-1
Hopf bifurcation in a CTL-inclusive HIV-1 infection model with two time delays
Viral dynamics model with CTL immune response incorporating antiretroviral therapy
Threshold virus dynamics with impulsive antiretroviral drug effects
A fractional-order model of HIV infection with drug therapy effect
An exponential matrix method for solving systems of linear differential equations
Stochastic model for Langerhans cells and HIV dynamics in vivo
Impact of gene-modified T cells on HIV infection dynamics
A latency fractional order model for HIV dynamics
HIV dynamics: analysis and robust multirate MPC-based treatment schedules
Modelling HIV dynamics with cell‐to‐cell transmission and CTL response
Global dynamics for viral infection model with Beddington-Deangelis functional response and an eclipse stage of infected cells
Stability and Hopf bifurcation in a delayed model for HIV infection of CD\(4^+\) T cells
The probability of HIV infection in a new host and its reduction with microbicides
Global properties of a class of HIV models
Emerging disease dynamics in a model coupling within-host and between-host systems
Stochastic model for in-host HIV dynamics with therapeutic intervention
Threshold dynamics and threshold analysis of HIV infection model with treatment
Dynamics of an HIV-1 therapy model of fighting a virus with another virus
Modelling hepatotoxicity and antiretroviral therapeutic effect in HIV/HBV coinfection
A model for coupling within-host and between-host dynamics in an infectious disease
Analyzing global stability of the delay viral model with general incidence rate
A delayed HIV-1 infection model with Beddington-DeAngelis functional response
A Bayesian approach for estimating antiviral efficacy in HIV dynamic models
Anti-viral drug treatment along with immune activator IL-2: a control-based mathematical approach for HIV infection
Optimal control of a time delayed HIV-1 infection model
Infection dynamics in HIV-specific CD4 T cells: does a CD4 T cell boost benefit the host or the virus?
Global dynamics of a delayed HIV-1 infection model with absorption and saturation infection
An age-structured virus model with two routes of infection in heterogeneous environments
Observability criteria for impulsive control systems with applications to biomedical engineering processes
Analysis of an HIV infection model with logistic target-cell growth and cell-to-cell transmission
A model incorporating combined RTIs and PIs therapy during early HIV-1 infection
Positive solutions to singular fractional differential system with coupled boundary conditions
The role of backward mutations on the within-host dynamics of HIV-1
Equivalence of the MTS method and CMR method for differential equations associated with semisimple singularity
Viral dynamics with immune responses: effects of distributed delays and Filippov antiretroviral therapy
Global dynamics of an HIV-1 infection model with distributed intracellular delays
Numerical modeling of fractional-order biological systems
Dynamics analysis of an HIV infection model including infected cells in an eclipse stage
Short and long period optimization of drug doses in the treatment of AIDS
A primary infection model for HIV and immune response with two discrete time delays
An intracellular delay-differential equation model of the HIV infection and immune control
Estimation of HIV/AIDS parameters.
Stationary distribution and probability density function analysis of a stochastic HIV model with cell-to-cell infection
Dynamics and asymptotical profiles of an age-structured viral infection model with spatial diffusion
Modelling the drugs therapy for HIV infection with discrete-time delay
Numerical analysis for a fractional differential time-delay model of HIV infection of CD4\(^+\) T-cell proliferation under antiretroviral therapy
On a coupled system of fractional compartmental models for a biological system
A stochastic delay model of HIV pathogenesis with reactivation of latent reservoirs
A stochastic HIV infection model with T-cell proliferation and CTL immune response
Dynamics of virus infection model with nonlytic immune response induced by stochastic noise
Dynamical behavior of a stochastic HIV model with logistic growth and Ornstein-Uhlenbeck process
Modelling a stochastic HIV model with logistic target cell growth and nonlinear immune response function
Impact of variability in stochastic models of bacteria-phage dynamics applicable to phage therapy
The threshold for a stochastic HIV-1 infection model with Beddington-DeAngelis incidence rate
On the solution of the human immunodeficiency virus (HIV) infection model using spectral collocation method
Dynamics of a stochastic HIV-1 infection model with logistic growth
A mathematical model of HIV-1 infection within host cell to cell viral transmissions with RTI and discrete delays
A delayed model for HIV infection incorporating intracellular delay
Parameter estimation and sensitivity analysis in an agent-based model of \textit{Leishmania major} infection
Global properties for a class of latent HIV infection dynamics model with CTL immune response
Modeling interleukin-2-based immunotherapy in AIDS pathogenesis
Dynamics of a stochastic cell-to-cell HIV-1 model with distributed delay
Reducing the latent CD4\(^+\) cells reservoirs in HIV infection with optimal HAART therapy
Stationary distribution and extinction of a stochastic HIV-1 infection model with distributed delay and logistic growth
A fractional calculus model for HIV dynamics: real data, parameter estimation and computational strategies
The effects of CTL immune response on HIV infection model with potent therapy, latently infected cells and cell-to-cell viral transmission
A collocation approach to solve the Riccati-type differential equation systems
A singularly perturbed HIV model with treatment and antigenic variation
Global stability analysis of HIV-1 infection model with three time delays
Analysis of HIV models with two time delays

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