A methodology for performing global uncertainty and sensitivity analysis in systems biology

From MaRDI portal

Publication:1797427

Jump to:navigation, search

DOI10.1016/j.jtbi.2008.04.011zbMath1400.92013WikidataQ37197756 ScholiaQ37197756MaRDI QIDQ1797427

Denise E. Kirschner, Christian J. Ray, Ian B. Hogue, Simeone Marino

Publication date: 22 October 2018

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc2570191

zbMATH Keywords

Monte Carlo methods; Latin hypercube sampling; epistemic uncertainty; agent-based model; sensitivity index; aleatory uncertainty; partial rank correlation coefficient; extended Fourier amplitude sensitivity test

Mathematics Subject Classification ID

62P10: Applications of statistics to biology and medical sciences; meta analysis

92B15: General biostatistics

92-02: Research exposition (monographs, survey articles) pertaining to biology

92C42: Systems biology, networks

Related Items

Unnamed Item, Mathematical analysis of an HTLV-I infection model with the mitosis of CD4+ T cells and delayed CTL immune response, Global dynamics of a stage-structured hantavirus infection model with seasonality, Dynamics of Infectious Diseases: Local Versus Global Awareness, Control of Nipah virus outbreak in commercial pig-farm with biosecurity and culling, AN AGE STRUCTURE MODEL WITH IMPULSE ACTIONS FOR LEPTOSPIROSIS IN LIVESTOCK CATTLE, A NONAUTONOMOUS MODEL FOR THE INTERACTIVE EFFECTS OF FEAR, REFUGE AND ADDITIONAL FOOD IN A PREY–PREDATOR SYSTEM, Modeling the impact of early case detection on dengue transmission: deterministic vs. stochastic, Application of Mathematical Epidemiology to Crop Vector-Borne Diseases: The Cassava Mosaic Virus Disease Case, Identifying the Dominant Transmission Pathway in a Multi-stage Infection Model of the Emerging Fungal Pathogen Batrachochytrium Salamandrivorans on the Eastern Newt, A nonautonomous mathematical model to assess the impact of algae on the abatement of atmospheric carbon dioxide, Assessing the impact of agrochemicals on schistosomiasis transmission: A mathematical study, Mathematical insights into neuroendocrine transdifferentiation of human prostate cancer cells, Modeling the effects of insecticides and external efforts on crop production, A mathematical model for the role of macrophages in the persistence and elimination of oncolytic viruses, Modeling the impact of host resistance on structured tick population dynamics, Examining HIV progression mechanisms via mathematical approaches, Dynamics analysis of an HIV infection model with latent reservoir, delayed CTL immune response and immune impairment, Modeling the recent outbreak of COVID-19 in India and its control strategies, Bifurcation from an Epidemic Model in the Presence of Memory Effects, Impacts of transpiration of agricultural crops and seeding on rainfall: Implications from a mathematical model, Rapid Bayesian Inference for Expensive Stochastic Models, Mathematical modelling of echinococcosis in human, dogs and sheep with intervention, Dynamic analysis of an HIV/AIDS treatment model incorporating MSM, Analysis and dynamical behavior of a novel dengue model via fractional calculus, Modeling the Importation and Local Transmission of Huanglongbing Disease: Bifurcation and Sensitivity Analysis, Asymptotic Properties and Stability Switch of a Delayed-Within-Host-Dengue Infection Model with Mitosis and Immune Response, A Delayed Eco-Epidemiological Model with Weak Allee Effect and Disease in Prey, AN ECOEPIDEMIC SEASONALLY FORCED MODEL FOR THE COMBINED EFFECTS OF FEAR, ADDITIONAL FOODS AND SELECTIVE PREDATION, A TUMOR-IMMUNE MODEL WITH MIXED IMMUNOTHERAPY AND CHEMOTHERAPY: QUALITATIVE ANALYSIS AND OPTIMAL CONTROl, Sensitivity analysis of chronic hepatitis C virus infection with immune response and cell proliferation, Mathematical Modeling for Schistosomiasis with Seasonal Influence: A Case Study in Hubei, China, TRANSMISSION DYNAMICS AND THE CONTROL OF HEPATITIS B IN CHINA: A POPULATION DYNAMICS VIEW, OPTIMAL CONTROL ANALYSIS OF THE EFFECT OF TREATMENT, ISOLATION AND VACCINATION ON HEPATITIS B VIRUS, MODELING ZIKA TRANSMISSION DYNAMICS: PREVENTION AND CONTROL, EFFECT OF TIME DELAY IN A CANNIBALISTIC STAGE-STRUCTURED PREDATOR–PREY MODEL WITH HARVESTING OF AN ADULT PREDATOR: THE CASE OF LIONFISH, Dynamical analysis of a mean-field vector-borne diseases model on complex networks: An edge based compartmental approach, Effect of Leakage Delay on Hopf Bifurcation in a Fractional BAM Neural Network, Theoretical assessment of the impact of desert aerosols on the dynamical transmission of meningitidis serogroup A, A MATHEMATICAL ANALYSIS OF ZIKA VIRUS EPIDEMIC IN RIO DE JANEIRO AS A VECTOR-BORNE AND SEXUALLY TRANSMITTED DISEASE, A CHOLERA METAPOPULATION MODEL INTERLINKING MIGRATION WITH INTERVENTION STRATEGIES — A CASE STUDY OF ZIMBABWE (2008–2009), Parameter and Uncertainty Estimation for Dynamical Systems Using Surrogate Stochastic Processes, Mathematical analysis of a tuberculosis model with imperfect vaccine, On the dynamics of a vaccination model with multiple transmission ways, Connecting local and global sensitivities in a mathematical model for wound healing, OPV Virus Evolution: Assessing the Risk of cVDPV Outbreak, Understanding biological control with entomopathogenic fungi—Insights from a stochastic pest–pathogen model, DYNAMICS OF AN INTRA-HOST MODEL OF MALARIA WITH A CONSTANT DRUG EFFICIENCY, SARS-CoV-2 and self-medication in Cameroon: a mathematical model, Mathematical Analysis of Diagnosis Rate Effects in Covid-19 Transmission Dynamics with Optimal Control, Determining reliable parameter estimates for within-host and within-vector models of Zika virus, A discrete-time risk-structured model of cholera infections in Cameroon, Dynamic analysis and optimal control of a class of SISP respiratory diseases, Time-varying sensitivity analysis of an influenza model with interventions, Dynamics of a delayed within host model for dengue infection with immune response and Beddington–DeAngelis incidence, Interactions of periodic birth and shearing induce outbreak of Brucellosis in Inner Mongolia, Global dynamics and bifurcation analysis of an insect-borne plant disease model with two transmission routes, A diffusive tuberculosis model with early and late latent infections: New Lyapunov function approach to global stability, Global dynamical analysis of H5 subtype avian influenza model, Dynamics of an epidemic model with imperfect vaccinations on complex networks, Combination therapy for cancer with IL-27 and anti-PD-1: A simplified mathematical model, MATHEMATICAL ANALYSIS OF TRANSMISSION DYNAMICS OF HIV/ AIDS IN RISK STRUCTURED POPULATION, Unnamed Item, Exploring how ecological and epidemiological processes shape multi-host disease dynamics using global sensitivity analysis, Modeling and multi-objective optimal control of reaction-diffusion COVID-19 system due to vaccination and patient isolation, Quantifying the Effects of Non-Pharmaceutical and Pharmaceutical Interventions Against Covid-19 Epidemic in the Republic of Korea: Mathematical Model-Based Approach Considering Age Groups and the Delta Variant, A reaction-diffusion epidemic model with virus mutation and media coverage: theoretical analysis and numerical simulation, Spatial movement with memory-induced cross-diffusion effect and toxin effect in predator, Penetration and distribution efficacy of chemotherapeutic drugs in biological tissues: a computational investigation, A minimal mathematical model to study insulin synthesis and secretion process, A perturbative approach to the analysis of many-compartment models characterized by the presence of waning immunity, Threshold dynamics of an almost periodic vector-borne disease model, A tumor-Immune interaction model with the effect of impulse therapy, A stochastic model of antibiotic misuse, economy, and drug resistance: relating mutant extinction probability to socioeconomic and epidemiological factors, Different mechanisms of CD200-CD200R induce diverse outcomes in cancer treatment, Treatment of leishmaniasis with chemotherapy and vaccine: a mathematical model, Theoretical assessment of the impact of awareness programs on cholera transmission dynamic, Effects of behaviour change on HFMD transmission, Unequal effects of SARS-CoV-2 infections: model of SARS-CoV-2 dynamics in Cameroon (Sub-Saharan Africa) versus New York State (United States), A continuation technique for maximum likelihood estimators in biological models, Generalized stressors on hive and forager bee colonies, Modeling COVID‐19: Forecasting and analyzing the dynamics of the outbreaks in Hubei and Turkey, Impact of Vaccination, Insecticide-Impregnated Collar, and Treatment on the Canine Leishmaniasis, GENERAL THEORY FOR SIGNIFICANCE OF CULLING IN TWO-WAY DISEASE TRANSMISSION BETWEEN HUMANS AND ANIMALS, A SEASONALLY FORCED ECO-EPIDEMIC MODEL WITH DISEASE IN PREDATOR AND INCUBATION DELAY, A coupled evolutionary model of the viral virulence in an SIS community, Global dynamics of a diffusive SEICR HCV model with nonlinear incidences, Optimal control of an influenza model with mixed cross-infection by age group, Effect of cross-border migration on the healthcare system of a destination community: insights from mathematical modelling of COVID-19 in a developing country, Assessing potential insights of an imperfect testing strategy: parameter estimation and practical identifiability using early COVID-19 data in India, Threshold dynamics of an HIV-1 model with both virus-to-cell and cell-to-cell transmissions, immune responses, and three delays, Threshold dynamics of a time-delayed epidemic model for continuous imperfect-vaccine with a generalized nonmonotone incidence rate, Mathematical modelling of COVID-19 dynamics using SVEAIQHR model, Inferring parameters of pyramidal neuron excitability in mouse models of Alzheimer's disease using biophysical modeling and deep learning, Global dynamics of a time-delayed nonlocal reaction-diffusion model of within-host viral infections, Mutations make pandemics worse or better: modeling SARS-CoV-2 variants and imperfect vaccination, A mathematical model of obesity-induced type 2 diabetes and efficacy of anti-diabetic weight reducing drug, A comprehensive and detailed within-host modeling study involving crucial biomarkers and optimal drug regimen for type I lepra reaction: a deterministic approach, Intraspecific competition of predator for prey with variable rates in protected areas, Modeling the dynamics of COVID-19 in Nigeria, A two-sex model of human papillomavirus infection: vaccination strategies and a case study, A virtual host model of \textit{Mycobacterium tuberculosis} infection identifies early immune events as predictive of infection outcomes, Mathematical modeling of algal blooms due to swine CAFOs in eastern North Carolina, Modelling the effects of ozone concentration and pulse vaccination on seasonal influenza outbreaks in Gansu Province, China, Optimal treatment strategies for delayed cancer-immune system with multiple therapeutic approach, Data-driven mathematical modeling and quantitative analysis of cell dynamics in the tumor microenvironment, An Ebola model with hyper-susceptibility, Phage-antibiotic synergy inhibited by temperate and chronic virus competition, Mathematical modeling of tumor and cancer stem cells treated with CAR-T therapy and inhibition of TGF-\(\beta\), Dynamics of an opinion model with threshold-type delay, An investigation of delay induced stability transition in nutrient-plankton systems, Bistability in a model of tumor-immune system interactions with an oncolytic viral therapy, Modeling of measles epidemic with optimized fractional order under Caputo differential operator, Optimal control strategy for cancer remission using combinatorial therapy: a mathematical model-based approach, Sensitivity analysis and optimal treatment control for a mathematical model of human papillomavirus infection, Modelling the impact of media-induced social distancing on the containment of COVID-19 in Beijing, Role of immunotherapy in tumor-immune interaction: perspectives from fractional-order modelling and sensitivity analysis, Mathematical modeling and analysis of the heat shock protein response during thermal stress in fish and HeLa cells, Disease control through removal of population using Z-control approach, Evaluating strategies for tuberculosis to achieve the goals of WHO in China: a seasonal age-structured model study, Modeling and analysis of a H1N1 model with relapse and effect of twitter, Dynamical analysis, optimum control and pattern formation in the biological pest (EFSB) control model, Modeling the transmission dynamics of malaria with saturated treatment: a case study of India, Mathematical modeling and projections of a vector-borne disease with optimal control strategies: a case study of the Chikungunya in Chad, Exploring dynamical properties of a type 1 diabetes model using sensitivity approaches, A mathematical model of immunomodulatory treatment in myocardial infarction, A multi-strain epidemic model for COVID-19 with infected and asymptomatic cases: application to French data, Multi-method global sensitivity analysis of mathematical models, Data-driven models for replication kinetics of \textit{Orthohantavirus} infections, Mathematical modeling and analysis of CD200-CD200R in cancer treatment, Threshold dynamics of an HIV-1 model with both viral and cellular infections, cell-mediated and humoral immune responses, Modelling and analysis of HFMD with the effects of vaccination, contaminated environments and quarantine in mainland China, Modeling the effect of antibiotic exposure on the transmission of methicillin-resistant \textit{Staphylococcus aureus} in hospitals with environmental contamination, Implication of sexual transmission of Zika on dengue and Zika outbreaks, Asymptotic analysis of endemic equilibrium to a brucellosis model, Transmission dynamics of brucellosis in Jilin province, China: effects of different control measures, Stochastic HIV model coupled with pharmacokinetics and drug adherence may explain intermittent viral blips, Model-based projection of Zika infection risk with temperature effect: a case study in Southeast Asia, Impact of the WHO integrated stewardship policy on the control of methicillin-resistant \textit{Staphyloccus aureus} and third-generation cephalosporin-resistant \textit{Escherichia coli}: using a mathematical modeling approach, Modeling the effect of gut microbiome on therapeutic efficacy of immune checkpoint inhibitors against cancer, Assessing age-specific vaccination strategies and post-vaccination reopening policies for COVID-19 control using SEIR modeling approach, Ranking non-pharmaceutical interventions against Covid-19 global pandemic using global sensitivity analysis -- effect on number of deaths, Sensitivity analysis methods in the biomedical sciences, Risk structured model of cholera infections in Cameroon, Mathematical modeling of the receptor-mediated endocytosis process of targeted therapeutic agents in drug delivery systems, Mathematical analysis of rabies infection, Sensitivity analysis of a strongly-coupled human-based electromechanical cardiac model: effect of mechanical parameters on physiologically relevant biomarkers, Dynamics of an HIV infection model with two infection routes and evolutionary competition between two viral strains, A nonautonomous model for the effect of environmental toxins on plankton dynamics, Use of global sensitivity analysis to assess the soil poroelastic parameter influence, Modeling the effects of meteorological factors and unreported cases on seasonal influenza outbreaks in Gansu Province, China, A framework for network-based epidemiological modeling of tuberculosis dynamics using synthetic datasets, Impact of venereal transmission on the dynamics of vertically transmitted viral diseases among mosquitoes, Increase hemoglobin level in severe malarial anemia while controlling parasitemia: a mathematical model, Mathematical modeling of public opinions: parameter estimation, sensitivity analysis, and model uncertainty using an agree-disagree opinion model, \textit{Shigellosis} dynamics: modelling the effects of treatment, sanitation, and education in the presence of carriers, Mathematical assessment of the role of environmental factors on the dynamical transmission of cholera, Dynamics and control of multidrug-resistant bacterial infection in hospital with multiple delays, Mathematical model of chronic dermal wounds in diabetes and obesity, Optimal control strategies of Zika virus model with mutant, Modeling the transmission of dengue infection through fractional derivatives, Dynamics of a seasonal brucellosis disease model with nonlocal transmission and spatial diffusion, Periodic oscillations in HIV transmission model with intracellular time delay and infection-age structure, Spatially antiviral dynamics determines HCV in vivo replication and evolution, Modelling the potential impact of social distancing on the COVID-19 epidemic in South Africa, Bifurcation and sensitivity analysis reveal key drivers of multistability in a model of macrophage polarization, Mathematical modeling of echinococcosis in humans, dogs, and sheep, A data-driven mathematical model of the heroin and fentanyl epidemic in Tennessee, Physiological insights into electrodiffusive maintenance of gastric mucus through sensitivity analysis and simulations, An investigation of tuberculosis progression revealing the role of macrophages apoptosis via sensitivity and bifurcation analysis, Mathematical modeling of the eyespots in butterfly wings, A Zika endemic model for the contribution of multiple transmission routes, Optimal control and cost-effectiveness analysis of a huanglongbing model with comprehensive interventions, To Sobol or not to Sobol? The effects of sampling schemes in systems biology applications, Mathematically modeling the effect of touch frequency on the environmental transmission of \textit{Clostridioides difficile} in healthcare settings, Preliminary prediction of the control reproduction number of COVID-19 in Shaanxi province, China, Disease clearance of tuberculosis infection: an in-host continuous-time Markov chain model, Stochastic modeling of imperfect \textit{Salmonella} vaccines in an adult dairy herd, Migration and orientation of endothelial cells on micropatterned polymers: a simple model based on classical mechanics, A mathematical model of effects of environmental contamination and presence of volunteers on hospital infections in China, Analysis of an in-host tuberculosis model for disease control, Modeling hantavirus infections in mainland China, An investigation on Monod-Haldane immune response based tumor-effector-interleukin-2 interactions with treatments, Mathematical analysis and clinical implications of an HIV model with adaptive immunity, Vector preference annihilates backward bifurcation and reduces endemicity, Modelling the host immune response to mature and immature dengue viruses, Complete dynamical analysis for a nonlinear HTLV-I infection model with distributed delay, CTL response and immune impairment, A mathematical model of tumor-immune interactions with an immune checkpoint inhibitor, A model to assess the effect of vaccine compliance on human papillomavirus infection and cervical cancer, Optimal control of methicillin-resistant \textit{Staphylococcus aureus} transmission in hospital settings, Overcoming drug resistance to BRAF inhibitor, Analysis of an HIV model with immune responses and cell-to-cell transmission, Mathematical modeling of cancer treatment with radiation and PD-L1 inhibitor, Global dynamics of an age-structured cholera model with both human-to-human and environment-to-human transmissions and saturation incidence, Chemical control for host-parasitoid model within the parasitism season and its complex dynamics, Optimal control of vaccination in a vector-Borne reaction-diffusion model applied to Zika virus, Analysis of a mathematical model for tuberculosis with diagnosis, Nonlinear pulse vaccination in an SIR epidemic model with resource limitation, The Vicodin abuse problem: a mathematical approach, Stability analysis of an HIV/AIDS epidemic model with sexual transmission in a patchy environment, Threshold dynamics in a clonorchiasis model with time delays, A stochastic dynamical model for nosocomial infections with co-circulation of sensitive and resistant bacterial strains, SIRC epidemic model with cross-immunity and multiple time delays, Modeling the influence of vaccination coverage on the dynamics of COVID‐19 pandemic with the effect of environmental contamination, Global dynamics and bifurcation analysis of a fractional‐order SEIR epidemic model with saturation incidence rate, Modeling mosquito control by an impulsive reaction-diffusion mosquito model with periodic evolution domain, A robust optimal control framework for controlling aberrant RTK signaling pathways in esophageal cancer, The role of tumor activation and inhibition with saturation effects in a mathematical model of tumor and immune system interactions undergoing oncolytic viral therapy, A tuberculosis model with early and late latency, imperfect vaccination, and relapse: An application to China, Understanding the interplay of CAR-NK cells and triple-negative breast cancer: insights from computational modeling, Reduced model for female endocrine dynamics: validation and functional variations, A mathematical model for the impact of disinfectants on the control of bacterial diseases, Model-based estimation of expected time to cholera extinction in Lusaka, Zambia, Quantitative assessment of a dual epidemic caused by tuberculosis and HIV in the Philippines, Dynamics of a cross-superdiffusive SIRS model with delay effects in transmission and treatment, A multiscale hybrid model for exploring the effect of Resolvin D1 on macrophage polarization during acute inflammation, Fractional dynamics of the transmission phenomena of dengue infection with vaccination, SENSITIVITY ANALYSIS AND IMPACT OF AN IMPERFECT VACCINE OF TWO STRAINS OF HEPATITIS B VIRUS INFECTION, TWO-FOLD IMPACTS OF FEAR IN A SEASONALLY FORCED PREDATOR–PREY SYSTEM WITH COSNER FUNCTIONAL RESPONSE, Statistical analysis of two-compartment pharmacokinetic models with drug non-adherence, A mathematical model of invasion and control of coconut rhinoceros beetle \textit{Oryctes rhinoceros (L.)} in Guam, Treatment of melanoma with dendritic cell vaccines and immune checkpoint inhibitors: a mathematical modeling study, A systematic study of autonomous and nonautonomous predator-prey models with combined effects of fear, migration and switching, IL-27 in combination with anti-PD-1 can be anti-cancer or pro-cancer, Dynamical behavior and density function of a stochastic model of HPV infection and cervical cancer with a case study for Xinjiang, China, Investigating the role of zooplankton in sustaining frog population, Automated translation and accelerated solving of differential equations on multiple GPU platforms, Optimal control of hepatitis B in a sub-Saharan African rural area, Mathematical modeling analysis and simulation of human papillomavirus infection and cervical cancer in Xinjiang, China, Dynamical modeling the effect of glucagon-like peptide on glucose-insulin regulatory system based on mice experimental observation, Edge-based compartmental modeling for the spread of cholera on random networks: a case study in Somalia, Mathematical assessment of the role of interventions against SARS-CoV-2, An application of the Grünwald-Letinkov fractional derivative to a study of drug diffusion in pharmacokinetic compartmental models, Mathematical analysis for the dynamics of snakebite envenoming, Dynamics of a two-patch SIR model with disease surveillance mediated infection force, Global dynamics of a space-age structured Covid-19 model coupling within-host infection and between-host transmission, Modeling of mouse experiments suggests that optimal anti-hormonal treatment for breast cancer is diet-dependent, Global analysis of an age-structured tuberculosis model with an application to Jiangsu, China, The tipping point: A mathematical model for the profit-driven abandonment of restaurant tipping, Sensitivity analysis for stochastic and deterministic models of nascent focal adhesion dynamics, A Seasonal Model for West Nile Virus, A simple in-host model for Mycobacterium tuberculosis that captures all infection outcomes, AN INTEGRATED PEST MANAGEMENT MODEL WITH DOSE-RESPONSE EFFECT OF PESTICIDES, THE “UNHOLY” CHIKUNGUNYA–DENGUE–ZIKA TRINITY: A THEORETICAL ANALYSIS, BISTABILITY ANALYSIS OF AN HIV MODEL WITH IMMUNE RESPONSE, MODELLING THE INTRODUCTION OF WOLBACHIA INTO AEDES AEGYPTI MOSQUITOES TO REDUCE DENGUE TRANSMISSION, Modelling and Sensitivity Analysis of COVID-19 Under the Influence of Environmental Pollution, Mathematical modeling of contact tracing as a control strategy of Ebola virus disease, Analysis of an HIV model with post-treatment control, MODELING AND DYNAMICS OF HIV TRANSMISSION AMONG HIGH-RISK GROUPS IN GUANGZHOU CITY, CHINA, HUMAN POPULATION EFFECTS ON THE ULSOOR LAKE FISH SURVIVAL, A mathematical model of cholera in a periodic environment with control actions, Global dynamics of a model of hepatitis B virus infection in a sub-Saharan African rural area, Nonlinear dynamical behavior of an SEIR mathematical model: Effect of information and saturated treatment, Dynamics of breast cancer under different rates of chemoradiotherapy, A population model capturing dynamics of tuberculosis granulomas predicts host infection outcomes, Quantifying the impact of decay in bed-net efficacy on malaria transmission, Modelling the transmission dynamics of dengue in the presence of \textit{Wolbachia}, Global sensitivity analysis used to interpret biological experimental results, Modelling the dynamics of CaMKII-NMDAR complex related to memory formation in synapses: the possible roles of threonine 286 autophosphorylation of CaMKII in long term potentiation, A mathematical study to control visceral leishmaniasis: an application to South Sudan, Numerical analysis of discrete switching prey-predator model for integrated pest management, Global sensitivity analysis of a model related to memory formation in synapses: model reduction based on epistemic parameter uncertainties and related issues, Dynamical analysis and control strategies in modeling anthrax, Analysis of a temperature- and rainfall-dependent model for malaria transmission dynamics, Complex dynamics and bifurcation analysis of host-parasitoid models with impulsive control strategy, Modeling ebola virus disease transmissions with reservoir in a complex virus life ecology, Mathematical analysis of a weather-driven model for the population ecology of mosquitoes, The potential impact of a prophylactic vaccine for Ebola in Sierra Leone, Modeling the host response to inhalation anthrax, Parameter inference for an individual based model of chytridiomycosis in frogs, Global sensitivity analysis of a mathematical model of acute inflammation identifies nonlinear dependence of cumulative tissue damage on host interleukin-6 responses, Modeling the effects of systemic mediators on the inflammatory phase of wound healing, A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment, Restoration of cytosolic calcium inhibits \textit{Mycobacterium tuberculosis} intracellular growth: theoretical evidence and experimental observation, Modeling approach influences dynamics of a vector-borne pathogen system, Cost-effectiveness evaluation of gender-based vaccination programs against sexually transmitted infections, A mathematical model studying mosquito-stage transmission-blocking vaccines, Global analysis of a Holling type II predator-prey model with a constant prey refuge, A dynamical system that describes vein graft adaptation and failure, The role of CD200-CD200R in tumor immune evasion, Stability analysis and optimal control for yellow fever model with vertical transmission, Mathematical modeling of retinal degeneration: aerobic glycolysis in a single cone, A dynamic model to assess human papillomavirus vaccination strategies in a heterosexual population combined with men who have sex with men, New global dynamical results and application of several SVEIS epidemic models with temporary immunity, Phase-specific cancer-immune model considering acquired resistance to therapeutic agents, Effects of incubation and gestation periods in a prey-predator model with infection in prey, A delay nonautonomous model for the impacts of fear and refuge in a three species food chain model with hunting cooperation, A fractional order approach to modeling and simulations of the novel COVID-19, Optimal voluntary vaccination of adults and adolescents can help eradicate hepatitis B in China, Mathematical modelling of autoimmune myocarditis and the effects of immune checkpoint inhibitors, Impact of estrogen population pharmacokinetics on a QSP model of mammary stem cell differentiation into myoepithelial cells, A co-infection model on TB - COVID-19 with optimal control and sensitivity analysis, Mathematical investigation into the role of macrophage heterogeneity on the temporal and spatio-temporal dynamics of non-small cell lung cancers, Adaptive behaviors and vaccination on curbing COVID-19 transmission: modeling simulations in eight countries, Breast cancer exosomal microRNAs facilitate pre-metastatic niche formation in the bone: a mathematical model, The impact of temperature and decay in insecticide-treated net efficacy on malaria prevalence and control, Basic reproduction ratio of a mosquito-borne disease in heterogeneous environment, An HIV stochastic model with cell-to-cell infection, B-cell immune response and distributed delay, Modeling tumour heterogeneity of PD-L1 expression in tumour progression and adaptive therapy, Modelling the impact of human population and its associated pressure on forest biomass and forest-dependent wildlife population, Stationary distribution and probability density for a stochastic SISP respiratory disease model with Ornstein-Uhlenbeck process, Modeling transmission dynamics of measles in Nepal and its control with monitored vaccination program, Multi-seasonal modelling of the African maize stalk borer with assessment of crop residue management, Modeling the effects of drugs of abuse on within-host dynamics of two HIV species, The effect of PrEP uptake and adherence on the spread of HIV in the presence of casual and long-term partnerships, Extinction and stationary distribution of stochastic predator-prey model with group defense behavior, Modelling of a drug resistant tuberculosis for the contribution of resistance and relapse in Xinjiang, China, Analysis of COVID-19 epidemic transmission trend based on a time-delayed dynamic model, Threshold dynamics and optimal control of a dengue epidemic model with time delay and saturated incidence, The Effects of HIV-1 Infection on Latent Tuberculosis, Mathematical analysis of the transmission dynamics of brucellosis among bison, A Stochastic Model of the Melanopsin Phototransduction Cascade, Intermittent Preventive Treatment (IPT) and the Spread of Drug Resistant Malaria, Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments, Data Assimilation in Brain Tumor Models, A Mathematical Model of Gene Therapy for the Treatment of Cancer, A MATHEMATICAL MODEL FOR THE TREATMENT OF AIDS-RELATED KAPOSI'S SARCOMA, DYNAMICS ANALYSIS OF A VACCINATION MODEL FOR HPV TRANSMISSION, Sensitivity and Robustness Analysis for Stochastic Model of Nanog Gene Regulatory Network, Theoretical assessment of the impact of environmental contamination on the dynamical transmission of polio, Techniques for grounding agent-based simulations in the real domain: a case study in experimental autoimmune encephalomyelitis, Concordance coefficients to measure the agreement among several sets of ranks, Mathematical analysis of the dynamical transmission of Neisseria meningitidis serogroup A, QUALITATIVE ASSESSMENT OF THE ROLE OF TEMPERATURE VARIATIONS ON MALARIA TRANSMISSION DYNAMICS, A Risk-Structured Mathematical Model of Buruli Ulcer Disease in Ghana, Modelling the spatiotemporal dynamics of chemovirotherapy cancer treatment, Effects of pesticide dose on Holling II predator–prey model with feedback control, A mathematical study to control Guinea worm disease: a case study on Chad, Dengue in the Philippines: model and analysis of parameters affecting transmission, Mathematical model to assess vaccination and effective contact rate impact in the spread of tuberculosis, Weather-driven malaria transmission model with gonotrophic and sporogonic cycles, The role of asymptomatic class, quarantine and isolation in the transmission of COVID-19, Collective escape and supratransmission phenomena in a nonlinear oscillators chain, MATHEMATICAL MODELING OF PANCREATIC CANCER TREATMENT WITH CANCER STEM CELLS, THE EFFECT OF STOCHASTIC VARIABILITY ON TRANSMISSION DYNAMICS OF ECHINOCOCCOSIS, A DELAY NONAUTONOMOUS PREDATOR–PREY MODEL FOR THE EFFECTS OF FEAR, REFUGE AND HUNTING COOPERATION, EFFECT OF ADDITIONAL FOOD ON PREDATOR–PREY INTERACTIONS WITH WATER-LEVEL FLUCTUATION, Analysis of spread and persistence for stream insects with winged adult stages, Campus quarantine (\textit{Fengxiao}) for curbing emergent infectious diseases: lessons from mitigating A/H1N1 in Xi'an, China, Modeling the inhibition of breast cancer growth by GM-CSF, Immune response to infection by Leishmania: a mathematical model, Unraveling the contribution of pancreatic beta-cell suicide in autoimmune type 1 diabetes, Optimal control for an age-structured model for the transmission of hepatitis B, Modelling the impact of vaccination on curtailing \textit{Haemophilus influenzae} serotype `a', Understanding PGE2, LXA4 and LTB4 balance during \textit{Mycobacterium tuberculosis} infection through mathematical model, Media coverage and hospital notifications: correlation analysis and optimal media impact duration to manage a pandemic, Interplay between insecticide-treated bed-nets and mosquito demography: implications for malaria control, Mathematical model of tumor-immune surveillance, Backward bifurcation and control in transmission dynamics of arboviral diseases, Global dynamics of a vaccination model for infectious diseases with asymptomatic carriers, Mathematical model of mycobacterium-host interaction describes physiology of persistence, A host stage-structured model of enzootic \textit{West Nile virus} transmission to explore the effect of avian stage-dependent exposure to vectors, Modelling weekly vector control against Dengue in the Guangdong Province of China, Mathematical model of three age-structured transmission dynamics of chikungunya virus, A delayed prey-predator system with prey subject to the strong Allee effect and disease, Mathematical modeling of liver fibrosis, Influence of concurrency, partner choice, and viral suppression on racial disparity in the prevalence of HIV infected women, A hybrid model of tumor-stromal interactions in breast cancer, Pulse HIV vaccination: feasibility for virus eradication and optimal vaccination schedule, Mars approach for global sensitivity analysis of differential equation models with applications to dynamics of influenza infection, A mathematical model of immune-system-melanoma competition, A mathematical model for selective differentiation of neural progenitor cells on micropatterned polymer substrates, An epidemiological model of Rift Valley fever with spatial dynamics, Uncertainty quantification in simulations of epidemics using polynomial chaos, Modeling the role of TGF-\(\beta\) in regulation of the Th17 phenotype in the LPS-driven immune system, The meaning of sensitivity functions in signaling pathways analysis, Glucose-lactate metabolic cooperation in cancer: insights from a spatial mathematical model and implications for targeted therapy, Holling type II predator-prey model with nonlinear pulse as state-dependent feedback control, A generic model for a single strain mosquito-transmitted disease with memory on the host and the vector, Global stability of an infection-age structured HIV-1 model linking within-host and between-host dynamics, Differential characteristics of primary infection and re-infection can cause backward bifurcation in HCV transmission dynamics, Analyzing transmission dynamics of cholera with public health interventions, Modeling the effects of augmentation strategies on the control of dengue fever with an impulsive differential equation, Optimal control and cost-effectiveness analysis of a three age-structured transmission dynamics of Chikungunya virus, Enhanced surveillance on food-borne disease outbreaks: dynamics of cross-contamination in biocidal wash procedure, An agent-based model of inflammation and fibrosis following particulate exposure in the lung, Transformed epithelial cells and fibroblasts/myofibroblasts interaction in breast tumor: a mathematical model and experiments, Modeling optimal intervention strategies for cholera, A network model for the short-term prediction of the evolution of cocaine consumption in Spain, Age-structured mathematical modeling approach to short-term diffusion of electronic commerce in Spain, Error-controlled global sensitivity analysis of ordinary differential equations, Modelling seasonal HFMD infections with the effects of contaminated environments in mainland China, Mathematical assessment of the role of Dengvaxia vaccine on the transmission dynamics of dengue serotypes, Optimal control strategies for dengue transmission in Pakistan, A simple SI-type model for HIV/AIDS with media and self-imposed psychological fear, Exploration of sexual dimorphism and inter-individual variability in multivariate parameter spaces for a pharmacokinetic compartment model, Analysis of a heroin epidemic model with saturated treatment function, Uncertainty and sensitivity analysis of a rift valley fever model, Interaction of tumor with its micro-environment: a mathematical model, Modeling basic aspects of bacterial resistance of Mycobacterium tuberculosis to antibiotics, Quantifying the metabolic contribution to photoreceptor death in retinitis pigmentosa via a mathematical model, Hopf bifurcation in a model of TGF-\(\beta\) in regulation of the Th17 phenotype, Optimal intervention strategy for prevention tuberculosis using a smoking-tuberculosis model, Mathematical model for alopecia areata, Continuum model of T-cell avidity: understanding autoreactive and regulatory T-cell responses in type 1 diabetes, Mathematical modeling of fungal infection in immune compromised individuals: the effect of back mutation on drug treatment, Inferring pathological states in cortical neuron microcircuits, Modulation of the camp response by \(\mathrm{G}\alpha _i\) and \(\mathrm{G}\beta \gamma \): a computational study of G protein signaling in immune cells, Modelling the activation of alkaline pH response transcription factor PacC in \textit{Aspergillus nidulans}: involvement of a negative feedback loop, Modelling the effects of environmental heterogeneity within the lung on the tuberculosis life-cycle, Predicting the second wave of COVID-19 in Washtenaw County, MI, Modeling the effect of HIV/AIDS stigma on HIV infection dynamics in Kenya, Persistent oscillations and backward bifurcation in a malaria model with varying human and mosquito populations: implications for control, Phase variation and host immunity against high molecular weight (HMW) adhesins shape population dynamics of nontypeable \textit{Haemophilus influenzae} within human hosts, Effects of CCN1 and macrophage content on glioma virotherapy: a mathematical model, Negative feedback contributes to the stochastic expression of the interferon-\(\beta\) gene in virus-triggered type I interferon signaling pathways, Mathematical analysis of a model for AVL-HIV co-endemicity, Identifying mechanisms of homeostatic signaling in fibroblast differentiation, Mathematical model for MRSA nasal carriage, A multiscale agent-based model for the investigation of E. coli K12 metabolic response during biofilm formation, Modeling the spread of Zika virus in a stage-structured population: effect of sexual transmission, Assessing the potential impact of \textit{Salmonella} vaccines in an endemically infected dairy herd, Viral dynamics of an HIV model with latent infection incorporating antiretroviral therapy, A model of interactions between radiation-induced oxidative stress, protein and DNA damage in \textit{Deinococcus radiodurans}, Parameter estimation and sensitivity analysis in an agent-based model of \textit{Leishmania major} infection, Mathematical model for glucose dependence of the local renin-angiotensin system in podocytes, Models to assess the effects of non-identical sex ratio augmentations of Wolbachia-carrying mosquitoes on the control of dengue disease, Combination therapies and intra-tumoral competition: insights from mathematical modeling, Bifurcations and limit cycles in cytosolic yeast calcium, Mathematical model and intervention strategies for mitigating tuberculosis in the Philippines, Optimal predator control policy and weak allee effect in a delayed prey-predator system, Mathematical model of MDR-TB and XDR-TB with isolation and lost to follow-up, Assessing the impact of the environmental contamination on the transmission of Ebola virus disease (EVD), Viral dynamics of an HTLV-I infection model with intracellular delay and CTL immune response delay, Combining two methods of global sensitivity analysis to investigate MRSA nasal carriage model, Mathematical modeling of visceral Leishmaniasis and control strategies, Feedback loops interlocked at competitive binding sites amplify and facilitate genetic oscillations, A framework for model analysis across multiple experiment regimes: investigating effects of zinc on \textit{Xylella fastidiosa} as a case study, Methods for determining key components in a mathematical model for tumor-immune dynamics in multiple myeloma, A new conceptual framework for the therapy by optimized multidimensional pulses of therapeutic activity. The case of multiple myeloma model, Modeling the impact of biolarvicides on malaria transmission, Computational modeling of synergistic interaction between \(\alpha\)V\(\beta\)3 integrin and VEGFR2 in endothelial cells: implications for the mechanism of action of angiogenesis-modulating integrin-binding peptides, Developing a temperature-driven map of the basic reproductive number of the emerging tick vector of lyme disease \textit{Ixodes scapularis} in Canada, Rheumatoid arthritis -- a mathematical model, Mathematical modeling in scheduling cancer treatment with combination of VEGF inhibitor and chemotherapy drugs, The effects of resource limitation on a predator-prey model with control measures as nonlinear pulses, Stochastic simulations of a multi-group compartmental model for Johne's disease on US dairy herds with test-based culling intervention, Modelling optimal delivery of bFGF to chronic wounds using ODEs, Global dynamics and applications of an epidemiological model for hepatitis C virus transmission in China, A metapopulation model for the population dynamics of anopheles mosquito, Mathematical modelling of bacterial meningitis transmission dynamics with control measures, Global dynamics of an avian influenza A(H7N9) epidemic model with latent period and nonlinear recovery rate, A pest control model with birth pulse and residual and delay effects of pesticides, Threshold dynamics of an HIV-1 virus model with both virus-to-cell and cell-to-cell transmissions, intracellular delay, and humoral immunity, Mathematical analysis of the transmission dynamics of the liver fluke, \textit{Opisthorchis viverrini}, An exploration of the role of asymptomatic infections in the epidemiology of dengue viruses through susceptible, asymptomatic, infected and recovered (SAIR) models, A hybrid multi-compartment model of granuloma formation and T cell priming in tuberculosis, Systems biology approaches for understanding cellular mechanisms of immunity in lymph nodes during infection, Modeling socio-demography to capture tuberculosis transmission dynamics in a low burden setting, A model for \textit{Vibrio cholerae} colonization of the human intestine, A comparison of random vs. chemotaxis-driven contacts of T cells with dendritic cells during repertoire scanning, Hypoxia inducible factors-mediated inhibition of cancer by GM-CSF: a mathematical model, Threshold conditions for integrated pest management models with pesticides that have residual effects, Optimal control on COVID-19 eradication program in Indonesia under the effect of community awareness, Bifurcation analysis of an age-structured SIRI epidemic model, Global stability of an HIV infection model with saturated CTL immune response and intracellular delay, A mathematical model for the impacts of face mask, hospitalization and quarantine on the dynamics of COVID-19 in India: deterministic vs. stochastic, Oncolytic viral therapies and the delicate balance between virus-macrophage-tumour interactions: a mathematical approach, Global dynamics of a delayed alcoholism model with the effect of health education, A closer look at the spreaders of COVID-19 in Wisconsin and the US, Uncertainty quantification guided robust design for nanoparticles' morphology, Research on college students' physical exercise trend based on compartment model, Stability analysis of a virulent code in a network of computers, Mathematical global dynamics and control strategies on \textit{Echinococcus multilocularis} infection, A multiscale model on hospital infections coupling macro and micro dynamics, To apprehend or not to apprehend: a mathematical model for ending student strikes in a university, The effect of reinfection with the same serotype on dengue transmission dynamics, Mathematical model of colitis-associated colon cancer, Predicting the HIV/AIDS epidemic and measuring the effect of mobility in mainland China, Simulating the potential role of media coverage and infected bats in the 2014 Ebola outbreak, Exosomal microRNA concentrations in colorectal cancer: a mathematical model, Analysis of an age-structured tuberculosis model with treatment and relapse, Modelling the effects of pest control with development of pesticide resistance, Stability and global sensitivity analysis for an agree-disagree model: partial rank correlation coefficient and Latin hypercube sampling methods, Modeling and control of the public opinion: an agree-disagree opinion model, The role of RdCVFL in a mathematical model of photoreceptor interactions, Human choice to self-isolate in the face of the COVID-19 pandemic: a game dynamic modelling approach, A mechanistic systems pharmacology modeling platform to investigate the effect of PD-L1 expression heterogeneity and dynamics on the efficacy of PD-1 and PD-L1 blocking antibodies in cancer, Assessing the effects of diagnostic sensitivity on schistosomiasis dynamics, Mathematical investigation of innate immune responses to lung cancer: the role of macrophages with mixed phenotypes, Modeling within-host viral dynamics: the role of CTL immune responses in the evolution of drug resistance, Natural killer cells recruitment in oncolytic virotherapy: a mathematical model, Modeling the relationship between antibody-dependent enhancement and disease severity in secondary dengue infection, The within-host viral kinetics of SARS-CoV-2, Global dynamics and optimal control of a cholera transmission model with vaccination strategy and multiple pathways, Mathematical modeling of ventilator-induced lung inflammation, Global sensitivity analysis informed model reduction and selection applied to a Valsalva maneuver model, Using sensitivity analysis to identify factors promoting higher versus lower infection prevalence in multi-host communities, Dynamical analysis of a nonlocal delayed and diffusive HIV latent infection model with spatial heterogeneity, Modeling the stem cell hypothesis: investigating the effects of cancer stem cells and TGF \(- \beta\) on tumor growth, Effects of zooplankton selectivity on phytoplankton in an ecosystem affected by free-viruses and environmental toxins, Mathematical analysis and simulation of a hepatitis B model with time delay: a case study for Xinjiang, China, A mathematical model of the four cardinal acid-base disorders, Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations, A new model of dengue fever in terms of fractional derivative, Modeling the effect of literacy and social media advertisements on the dynamics of infectious diseases, Mathematical modeling of COVID-19 transmission: the roles of intervention strategies and lockdown, Modeling citrus Huanglongbing transmission within an orchard and its optimal control, Effect of delay in diagnosis on transmission of COVID-19, Experimental data and PBPK modeling quantify antibody interference in PEGylated drug carrier delivery, Modeling the effects of insects and insecticides on agricultural crops with NSFD method, Mathematical model of the immune response to dengue virus, Modeling the cell-to-cell transmission dynamics of viral infection under the exposure of non-cytolytic cure, A time-delayed SVEIR model for imperfect vaccine with a generalized nonmonotone incidence and application to measles, Analysis of an age-structured model for HIV-TB co-infection, Fitting thermodynamic-based models: incorporating parameter sensitivity improves the performance of an evolutionary algorithm, A novel nonlocal partial differential equation model of endothelial progenitor cell cluster formation during the early stages of vasculogenesis, Global dynamics of a delayed latent virus model with both virus-to-cell and cell-to-cell transmissions and humoral immunity, Long-term forecast of HIV/AIDS epidemic in China with fear effect and 90-90-90 strategies, A combination therapy of oncolytic viruses and chimeric antigen receptor T cells: a mathematical model proof-of-concept, Optimal control and cost-effectiveness analysis of a new COVID-19 model for omicron strain, Mathematical analysis of a delayed HIV infection model with saturated CTL immune response and immune impairment, Modeling and dynamic analysis of novel coronavirus pneumonia (COVID-19) in China, Epidemics and underlying factors of multiple-peak pattern on hand, foot and mouth disease in Wenzhou, China, Modelling the potential role of media campaigns on the control of listeriosis, Mathematical modeling of the influence of cultural practices on cholera infections in Cameroon, Geometric singular perturbation of a nonlocal partially degenerate model for \textit{Aedes aegypti}, An optimal control problem for dengue transmission model with \textit{Wolbachia} and vaccination, Algorithms and methodological challenges in the development and application of quantitative systems pharmacology models: a case study in type 2 diabetes, Check your assumptions: further scrutiny of basic model frameworks of antimicrobial resistance, Assessing the impact of insecticide-treated nets in the face of insecticide resistance on malaria control, Modeling of ionizing radiation induced hair follicle regenerative dynamics, Computational modeling implicates protein scaffolding in p38 regulation of akt, Mathematical modeling of tumor growth and treatment: triple negative breast cancer, Dynamics and strategies evaluations of a novel reaction-diffusion COVID-19 model with direct and aerosol transmission, Modeling COVID-19 dynamic using a two-strain model with vaccination, Mathematical analysis and sensitivity assessment of HIV/AIDS-Listeriosis co-infection dynamics, Mathematical modeling for the combination treatment of IFN-\(\gamma\) and anti-PD-1 in cancer immunotherapy, Role of senescent tumor cells in building a cytokine shield in the tumor microenvironment: mathematical modeling, A mathematical model of the within-host kinetics of SARS-CoV-2 neutralizing antibodies following COVID-19 vaccination, Systematic Bayesian posterior analysis guided by Kullback-Leibler divergence facilitates hypothesis formation, Mathematical modeling of the population dynamics of age-structured criminal gangs with correctional intervention measures, Local and global sensitivity analysis of spheroid and xenograft models of the acid-mediated development of tumor malignancy, Stochastic target-mediated drug disposition model based on birth-death process and its parameter inference using approximate Bayesian computation-MCMC, A Fokker-Planck feedback control framework for optimal personalized therapies in colon cancer-induced angiogenesis, Modeling the dynamics of heroin and illicit opioid use disorder, treatment, and recovery, Global analysis of tuberculosis dynamical model and optimal control strategies based on case data in the United States

Cites Work

Retrieved from "https://portal.mardi4nfdi.de/w/index.php?title=Publication:1797427&oldid=14157208"