Stochastic target-mediated drug disposition model based on birth-death process and its parameter inference using approximate Bayesian computation-MCMC

DOI10.1016/J.APM.2021.12.032MaRDI QIDQ2109866zbMATH OpenOpenAlexFDO

Authors Jong Hyuk Byun, Il Hyo Jung

Publication date 21 December 2022

Published in Applied Mathematical Modelling (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1016/j.apm.2021.12.032

zbMATH Keywords

pharmacokineticsglobal sensitivity analysiscontinuous time Markov chainapproximation Bayesian computationtarget-mediated drug disposition model

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Applications of branching processes (60J85) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Cites work

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• Sensitivity Analysis in Practice
• Stochastic differential mixed-effect models
• Stochastic vs. deterministic uptake of dodecanedioic acid by isolated rat livers

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• Monolix

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