Systems biology approaches for understanding cellular mechanisms of immunity in lymph nodes during infection

DOI10.1016/J.JTBI.2011.06.037MaRDI QIDQ1786429zbMATH OpenOpenAlexWikidataFDO

Authors Henry P. Mirsky, Mark J. Miller, Jennifer J. Linderman, Denise E. Kirschner

Publication date 24 September 2018

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc4504675

zbMATH Keywords

Markov modelsagent-based modelsdendritic cellscellular-Potts modelstwo-photon microscopy

Mathematics Subject Classification ID

Medical applications (general) (92C50) Systems biology, networks (92C42) Research exposition (monographs, survey articles) pertaining to biology (92-02) Cell biology (92C37)

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Cited in

(6)

• Quantitative measurements in 3-dimensional datasets of mouse lymph nodes resolve organ-wide functional dependencies
• Spatial modeling of HIV cryptic viremia and 2-LTR formation during raltegravir intensification
• T cell and reticular network co-dependence in HIV infection
• A time delay model of tumour-immune system interactions: global dynamics, parameter estimation, sensitivity analysis
• Insights from mathematical modelling for T cell migration into the central nervous system
• Physiological factors leading to a successful vaccination: a computational approach

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