A multiscale hybrid model for exploring the effect of Resolvin D1 on macrophage polarization during acute inflammation

DOI10.1016/J.MBS.2023.108997zbMATH Open1519.92052MaRDI QIDQ6167794FDOQ6167794

Authors: Jeroen F. Uleman, Emiliano Mancini, Rushd F. M. Al-Shama, Anje A. te Velde, Aletta D. Kraneveld, F. Castiglione 

Publication date: 7 August 2023

Published in: Mathematical Biosciences (Search for Journal in Brave)

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zbMATH Keywords

agent-based modelmultiscale modelgene-regulatory networkacute inflammationmacrophage polarizationResolvin D1

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Pathology, pathophysiology (92C32)

Cites Work

• Mechanistic simulations of inflammation: current state and future prospects
• A methodology for performing global uncertainty and sensitivity analysis in systems biology
• Application of formal methods to biological regulatory networks: extending Thomas' asynchronous logical approach with temporal logic
• On the use of the Hill functions in mathematical models of gene regulatory networks
• Understanding and comparisons of different sampling approaches for the Fourier amplitudes sensitivity test (FAST)
• The dynamics of acute inflammation
• Mathematical modelling of immune response in tissues

Cited In (5)

• From inflammation to wound healing: using a simple model to understand the functional versatility of murine macrophages
• The resolution of inflammation: a mathematical model of neutrophil and macrophage interactions
• Pro-inflammatory-anti - inflammatory cytokine dynamics mediated by cytokine-receptor dynamics in monocytes
• Macrophage anti-inflammatory behaviour in a multiphase model of atherosclerotic plaque development
• Modelling the continuum of macrophage phenotypes and their role in inflammation

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