An investigation of tuberculosis progression revealing the role of macrophages apoptosis via sensitivity and bifurcation analysis

DOI10.1007/s00285-021-01655-6zbMath1479.34087MaRDI QIDQ2232136

Federico Frascoli, Leif Ellingson, Jane M. Heffernan, Wenjing Zhang

Publication date: 4 October 2021

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-021-01655-6

zbMATH Keywords

disease progression; in-host tuberculosis infection model; sensitivity analysis and bifurcation analysis; tuberculosis treatments

Mathematics Subject Classification ID

93B35: Sensitivity (robustness)

34C05: Topological structure of integral curves, singular points, limit cycles of ordinary differential equations

34C20: Transformation and reduction of ordinary differential equations and systems, normal forms

34C23: Bifurcation theory for ordinary differential equations

92C50: Medical applications (general)

34D20: Stability of solutions to ordinary differential equations

34C60: Qualitative investigation and simulation of ordinary differential equation models

92C60: Medical epidemiology

Uses Software

• MATCONT

Cites Work

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• MATCONT
• CLOSED-FORM CONDITIONS OF BIFURCATION POINTS FOR GENERAL DIFFERENTIAL EQUATIONS