A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment

DOI10.1016/j.jtbi.2014.11.021zbMath1412.92178OpenAlexW2036084890WikidataQ28649754 ScholiaQ28649754MaRDI QIDQ2415779

Joshua T. Mattila, Véronique Dartois, J. Russell Butler, Denise E. Kirschner, Joanne Flynn, Jennifer J. Linderman, Philana Ling Lin, Elsje Pienaar, Nicholas A. Cilfone

Publication date: 23 May 2019

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2014.11.021

zbMATH Keywords

pharmacokineticspharmacodynamicsagent based modelgranulomaantibiotic gradients

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Medical epidemiology (92C60)

Related Items

Modelling the effects of environmental heterogeneity within the lung on the tuberculosis life-cycle ⋮ Modeling nanoparticle delivery of TB drugs to granulomas ⋮ Mathematical modeling and systems pharmacology of tuberculosis: isoniazid as a case study

Cites Work

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• Identifying control mechanisms of granuloma formation during \textit{M. tuberculosis} infection using an agent-based model
• A model of isoniazid treatment of tuberculosis

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