Backward bifurcation and control in transmission dynamics of arboviral diseases

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Publication:310012

DOI10.1016/J.MBS.2016.06.002zbMATH Open1347.34073arXiv1509.04919OpenAlexW2963798344WikidataQ40692611 ScholiaQ40692611MaRDI QIDQ310012FDOQ310012


Authors: H. Abboubakar, Jean Claude Kamgang, Daniel Tieudjo Edit this on Wikidata


Publication date: 7 September 2016

Published in: Mathematical Biosciences (Search for Journal in Brave)

Abstract: In this paper, we derive and analyze a compartmental model for the control of arboviral diseases which takes into account an imperfect vaccine combined with individual protection and some vector control strategies already studied in the literature. After the formulation of the model, a qualitative study based on stability analysis and bifurcation theory reveals that the phenomenon of backward bifurcation may occur. The stable disease-free equilibrium of the model coexists with a stable endemic equilibrium when the reproduction number, R 0 , is less than unity. Using Lyapunov function theory, we prove that the trivial equilibrium is globally asymptotically stable; When the disease-- induced death is not considered, or/and, when the standard incidence is replaced by the mass action incidence, the backward bifurcation does not occur. Under a certain condition , we establish the global asymptotic stability of the disease--free equilibrium of the full model. Through sensitivity analysis, we determine the relative importance of model parameters for disease transmission. Numerical simulations show that the combination of several control mechanisms would significantly reduce the spread of the disease, if we maintain the level of each control high, and this, over a long period.


Full work available at URL: https://arxiv.org/abs/1509.04919




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