Systematic Bayesian posterior analysis guided by Kullback-Leibler divergence facilitates hypothesis formation

DOI10.1016/j.jtbi.2022.111341zbMath1504.92044OpenAlexW4308372269WikidataQ122600951 ScholiaQ122600951MaRDI QIDQ2109318

Senta K. Georgia, Holly A. Huber, Stacey D. Finley

Publication date: 20 December 2022

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2022.111341

zbMATH Keywords

mathematical modelKullback-Leibler divergenceBayesian inferencesignal transductionposterior analysispancreatic beta cellsuppressor of cytokine signaling

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Cell biology (92C37) Systems biology, networks (92C42)

Uses Software

• Scikit

Cites Work

• Unnamed Item
• How Bayesian analysis cracked the red-state, blue-state problem
• An introduction to MCMC for machine learning
• Bayesian experimental design: A review
• A methodology for performing global uncertainty and sensitivity analysis in systems biology
• High-dimensional Bayesian parameter estimation: case study for a model of JAK2/STAT5 signaling
• Markov Chain Monte Carlo Convergence Diagnostics: A Comparative Review
• Probability Theory
• On Information and Sufficiency

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