Systematic Bayesian posterior analysis guided by Kullback-Leibler divergence facilitates hypothesis formation

DOI10.1016/J.JTBI.2022.111341MaRDI QIDQ2109318zbMATH OpenOpenAlexWikidataFDO

Authors Holly A. Huber, Senta K. Georgia, Stacey D. Finley

Publication date 20 December 2022

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

Full work available at URL https://doi.org/10.1016/j.jtbi.2022.111341

zbMATH Keywords

Bayesian inferenceKullback-Leibler divergencemathematical modelsignal transductionposterior analysispancreatic beta cellsuppressor of cytokine signaling

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42) Cell biology (92C37)

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Cites work

• A methodology for performing global uncertainty and sensitivity analysis in systems biology
• An introduction to MCMC for machine learning
• Bayesian experimental design: A review
• High-dimensional Bayesian parameter estimation: case study for a model of JAK2/STAT5 signaling
• How Bayesian analysis cracked the red-state, blue-state problem
• Markov Chain Monte Carlo Convergence Diagnostics: A Comparative Review
• On Information and Sufficiency
• Probability Theory
• Scikit-learn: machine learning in Python

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Uses Software

• Scikit

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