Asymmetric division of activated latently infected cells may explain the decay kinetics of the HIV-1 latent reservoir and intermittent viral blips

From MaRDI portal
Publication:1013286

DOI10.1016/j.mbs.2008.10.006zbMath1158.92028OpenAlexW2039370209WikidataQ37133236 ScholiaQ37133236MaRDI QIDQ1013286

Libin Rong, Alan S. Perelson

Publication date: 17 April 2009

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc2657607




Related Items

Spatiotemporal dynamics for a diffusive HIV-1 infection model with distributed delays and CTL immune responseDynamics of an HIV model with cytotoxic T-lymphocyte memoryDynamics of an HIV model with multiple infection stages and treatment with different drug classesModeling HIV persistence, the latent reservoir, and viral blipsViral dynamics of an HIV model with latent infection incorporating antiretroviral therapyStochastic modelling of viral blips in HIV-1-infected patients: effects of inhomogeneous density fluctuationsAnalysis of HIV latent infection model with multiple infection stages and different drug classesStability and Hopf bifurcation in a delayed HIV infection model with general incidence rate and immune impairmentMathematical analysis of a class of HIV infection models of \(\mathrm{CD4}^{+}\) T-cells with combined antiretroviral therapyDynamics analysis of an HIV infection model with latent reservoir, delayed CTL immune response and immune impairmentDynamics of an HIV infection model with virus diffusion and latently infected cell activationBackward bifurcations, turning points and rich dynamics in simple disease modelsQualitative analysis of a generalized virus dynamics model with both modes of transmission and distributed delaysOptimal control in HIV chemotherapy with termination viral load and latent reservoirStochastic HIV model coupled with pharmacokinetics and drug adherence may explain intermittent viral blipsGlobal exponential stability of a delayed HIV infection model with a nonlinear incidence rateStability and Hopf bifurcation of HIV-1 model with Holling II infection rate and immune delayDynamics of the HIV infection under antiretroviral therapy: a cellular automata approachModeling Pharmacodynamics on HIV Latent Infection: Choice of Drugs is Key to Successful Cure via Early TherapyStochastic modeling and simulation of viral evolutionTowards a new combination therapy with vectored immunoprophylaxis for HIV: modeling ``Shock and kill strategyHIV infection dynamics and viral rebound: modeling results from humanized miceAsymptotical profiles of a viral infection model with multi-target cells and spatial diffusionA model of HIV-1 infection with two time delays: mathematical analysis and comparison with patient dataAnalysis of an HIV infection model incorporating latency age and infection ageAndronov-Hopf bifurcation and sensitivity analysis of a time-delay HIV model with logistic growth and antiretroviral treatmentA stochastic HIV infection model with latent infection and antiretroviral therapyAnalysis of HIV models with two time delaysAn HIV model with age-structured latently infected cellsConflict and accord of optimal treatment strategies for HIV infection within and between hostsMathematical analysis of an HIV latent infection model including both virus-to-cell infection and cell-to-cell transmissionMathematical analysis of an HIV model with latent reservoir, delayed CTL immune response and immune impairmentGlobal dynamics and cost-effectiveness analysis of HIV pre-exposure prophylaxis and structured treatment interruptions based on a multi-scale modelGlobal dynamics of a latent HIV infection model with general incidence function and multiple delaysGLOBAL PROPERTIES FOR A CLASS OF LATENT HIV INFECTION DYNAMICS MODEL WITH CTL IMMUNE RESPONSELatently infected cell activation: a way to reduce the size of the HIV reservoir?Immuno-modulatory strategies for reduction of HIV reservoir cellsImpact of latently infected cells on strain archiving within HIV hostsDynamical analysis of antigen-driven t-cell infection model with multiple delaysInfluence of raltegravir intensification on viral load and 2-LTR dynamics in HIV patients on suppressive antiretroviral therapyBISTABILITY ANALYSIS OF AN HIV MODEL WITH IMMUNE RESPONSEDynamics and asymptotical profiles of an age-structured viral infection model with spatial diffusionDynamics of a new HIV model with the activation status of infected cellsA delay model for persistent viral infections in replicating cellsModeling within-host viral dynamics: the role of CTL immune responses in the evolution of drug resistanceStudying HIV latency by modeling the interaction between HIV proteins and the innate immune responseStochastic population switch may explain the latent reservoir stability and intermittent viral blips in HIV patients on suppressive therapyThe effects of CTL immune response on HIV infection model with potent therapy, latently infected cells and cell-to-cell viral transmissionAnalysis of an HIV model with post-treatment controlUnnamed ItemEFFECTS OF ECLIPSE PHASE AND DELAY ON THE DYNAMICS OF HIV INFECTIONAndronov-Hopf and Neimark-Sacker bifurcations in time-delay differential equations and difference equations with applications to models for diseases and animal populationsSpatial and temporal dynamics of a viral infection model with two nonlocal effectsModeling the role of macrophages in HIV persistence during antiretroviral therapyAnalysis and optimal control of an HIV model with logistic growth and infected cells in eclipse phase



Cites Work


This page was built for publication: Asymmetric division of activated latently infected cells may explain the decay kinetics of the HIV-1 latent reservoir and intermittent viral blips